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HPV vaccine hesitancy in the United States.
Curr Opin Pediatr
January 2025
Section of Hospital Medicine, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Purpose Of Review: Human papillomavirus (HPV) is the most common STI and accounts for roughly 37 000 HPV-associated cancers annually in the United States. Despite documented safety and effectiveness of the HPV vaccine, vaccination rates should be higher. We summarize literature surrounding vaccine hesitancy, a main reason for suboptimal vaccine coverage.
View Article and Find Full Text PDFOngoing Symptoms and Concerns Experienced by Low-Risk Breast Cancer Survivors Following Active Treatment.
Ann Surg Oncol
January 2025
Department of Surgery, School of Medicine and Public Health, Wisconsin Surgical Outcomes Research Program, University of Wisconsin, Madison, WI, USA.
Introduction: Little is known about the symptom burden of breast cancer survivors with early-stage disease. Many studies have focused on symptoms of patients who are undergoing or recently completed systemic therapy. However, with the increased use of Oncotype DX, the proportion of early-stage hormone receptor-positive patients who undergo chemotherapy has declined, making existing studies of the symptom experience less useful for these patients.
View Article and Find Full Text PDFPhalloplasty is one of the most complex procedures in plastic surgery. The criteria for an ideal neophallus include an aesthetic and erogenous phallus that allows for sexual intercourse, with a functional neo-urethra enabling standing urination. The free forearm flap has become the gold standard for phallic reconstruction.
View Article and Find Full Text PDFEmerging insights into the genetics and evolution of human same-sex sexual behavior.
Trends Genet
January 2025
Centre for Psychology and Evolution, School of Psychology, University of Queensland, Queensland, Australia.
Thanks to twin studies, it has been known for decades that human same-sex sexual behavior (SSB) has a substantial heritable component. However, only recently have large genome-wide association studies (GWAS) begun to illuminate the complex genetics involved. These studies have established that SSB is influenced by many common genetic variants, each with tiny but cumulative effects.
View Article and Find Full Text PDFThe developmental and genetic basis of male genitalia evolution in Drosophilids.
Curr Opin Insect Sci
January 2025
Department of Genetics and Developmental Biology, The Rappaport Faculty of Medicine and Research Institute, Technion - Israel Institute of Technology, Haifa 3109601, Israel. Electronic address:
Reproductive organs are among the most variable and rapidly evolving structures in the animal kingdom, probably due to sexual selection. In insects, the diverse morphology of male genitalia is often one of the few visible characteristics that can reliably distinguish closely related species, making it crucial for taxonomic classification. Consistent with this, males of the model organism Drosophila melanogaster and its closely related species display remarkable variations in genital morphology.
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