A novel experimental scheme has been developed in order to measure the heat capacity of mass selected clusters. It is based on controlled sticking of atoms on clusters. This allows one to construct the caloric curve, thus determining the melting temperature and the latent heat of fusion in the case of first-order phase transitions. This method is model-free. It is transferable to many systems since the energy is brought to clusters through sticking collisions. As an example, it has been applied to Na(90) (+) and Na(140) (+). Our results are in good agreement with previous measurements.
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http://dx.doi.org/10.1063/1.3000628 | DOI Listing |
Biomed Phys Eng Express
January 2025
Shandong Normal University, Jinan, Jinan, Shandong, 250014, CHINA.
In the medical field, endoscopic video analysis is crucial for disease diagnosis and minimally invasive surgery. The Endoscopic Foundation Models (Endo- FM) utilize large-scale self-supervised pre-training on endoscopic video data and leverage video transformer models to capture long-range spatiotemporal dependencies. However, detecting complex lesions such as gastrointestinal metaplasia (GIM) in endoscopic videos remains challenging due to unclear boundaries and indistinct features, and Endo-FM has not demonstrated good performance.
View Article and Find Full Text PDFJCO Precis Oncol
January 2025
McGill University Faculty of Medicine, Montréal, QC, Canada.
Purpose: MAP2K1/MEK1 mutations are potentially actionable drivers in cancer. MAP2K1 mutations have been functionally classified into three groups according to their dependency on upstream RAS/RAF signaling. However, the clinical efficacy of mitogen-activated protein kinase (MAPK) pathway inhibitors (MAPKi) for MAP2K1-mutant tumors is not well defined.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
The University of Oklahoma, Chemistry and Biochemistry, 101 Stephenson Parkway, 73019, Norman, UNITED STATES OF AMERICA.
Phototherapy - which includes photothermal therapy (PTT) and photodynamic therapy (PDT) - has evoked interest as a promising cancer treatment modality on account of its noninvasiveness, spatiotemporal precision, and minimal side effects. C. Wang et al.
View Article and Find Full Text PDFPLoS One
January 2025
Institute of Behavioural Neuroscience, Department of Experimental Psychology, Division of Psychology and Language Sciences, University College London, London, United Kingdom.
Virtual reality environments presented on tablets and smartphones offer a novel way of measuring navigation skill and predicting real-world navigation problems. The extent to which such virtual tests are effective at predicting navigation in older populations remains unclear. We compared the performance of 20 older participants (54-74 years old) in wayfinding tasks in a real-world environment in London, UK, and in similar tasks designed in a mobile app-based test of navigation (Sea Hero Quest).
View Article and Find Full Text PDFPLoS Negl Trop Dis
January 2025
Research Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Background: The Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is known for its capacity to cause severe neurological disease in Asia. Neurotropic flaviviruses within the Japanese encephalitis (JE) serogroup possess the distinctive feature of expressing a unique nonstructural protein, NS1'. The NS1' protein consists of the full NS1 protein with an additional 52 amino acid extension at the C-terminus and has been demonstrated to exhibit virulence in mammalian hosts upon infection.
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