A novel pressure-driven piezodispenser for nanoliter volumes.

Rev Sci Instrum

Genomation Laboratory, University of Washington, P.O. Box 352500, Seattle, Washington 98195-2500, USA.

Published: August 2008

A successful dispensing device has been built for use in biotechnology applications requiring nanoliter volume liquid transfer. Air pressure is used as the primary driving force and is controlled via a high speed miniature solenoid valve as opposed to many existing systems that use a valve in line with constantly pressurized fluid to start and stop the dispensing action. This automated pressure-driven system is used to improve a typical piezodriven microdispenser. The resulting system is much less prone to failures resulting from air entrainment and can dispense much higher viscosity fluids than the microdispenser alone.

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http://dx.doi.org/10.1063/1.2969658DOI Listing

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