AI Article Synopsis
- A 55-year-old woman with rapid gait difficulties that led to wheelchair use was admitted to a neurology ward.
- Investigations included various tests such as electroneuromyography and blood tests to identify her condition.
- She was diagnosed with POEMS syndrome, a rare disorder, and treated with high-dose chemotherapy and stem-cell transplantation.
Article Abstract
Background: A 55-year-old woman with no remarkable medical history presented to a neurology ward with a 17-week history of rapidly progressive gait difficulties that confined her to a wheelchair.
Investigations: Electroneuromyography, immunoelectrophoresis, bone radiography, lesion-targeted bone-marrow examination, blood tests.
Diagnosis: Neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome.
Management: High-dose chemotherapy and autologous hematopoietic stem-cell transplantation.
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| http://dx.doi.org/10.1038/ncpneuro0942 | DOI Listing |
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