Ms identification of microcystin-LR chlorination by-products.

Chemosphere

Environment and Health Laboratory (LERES), School of Public Health (EHESP), Avenue Professeur Léon-Bernard, CS 74312, 35043 Rennes Cedex, France.

Published: February 2009

Drinking water disinfection by chlorine is known to reduce concentration of microcystin, but compounds formed are rarely considered. In this work the chlorination of microcystin-LR has been studied by monitoring reactants consumption and reaction products using the linear trap quad-Orbitrap (LTQ-Orbitrap) technology. Microcystin-LR was totally transformed within 2 min, meanwhile chlorine was consumed until 30 min with a rate of 12 mol per mol of toxin. Four new by-products of microcystin-LR were identified as well as their isomers: monochloro-microcystin, monochloro-dihydroxy-microcystin, dichloro-dihydroxy-microcystin and trichloro-hydroxy-microcystin. In addition, four new isomers were also observed, corresponding to the dihydroxy-microcystin already known. Besides, another compound previously observed was identified as monochloro-hydroxy-microcystin.

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http://dx.doi.org/10.1016/j.chemosphere.2008.10.024DOI Listing

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