Serum thyroglobulin determination plays a central role, in combination with neck ultrasonography, in the follow-up of thyroid cancer patients. Its specificity is improved by thyroid remnant ablation, and its sensitivity is optimal following prolonged withdrawal or stimulation with recombinant human thyroid-stimulating hormone (TSH). Modern methods with an improved functional sensitivity may facilitate its use during follow-up.
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| http://dx.doi.org/10.1016/j.beem.2008.09.015 | DOI Listing |
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