Aims: To estimate the cost-effectiveness of three behavioral interventions provided to enhance hepatitis A virus (HAV) and hepatitis B virus (HBV) joint vaccination (HAV/HBV) compliance among homeless persons living in Los Angeles County.

Scope: A cost-effectiveness analysis (CEA) based on data from a randomized trial where the costs and compliance data from the trial are incorporated into two Markov models, simulating the natural history of acute and chronic hepatitis infection, following HAV/HBV vaccination.

Conclusions: Reductions in HBV-related disease is cost-effective to society and is associated with substantial improvements in quality of life.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772200PMC
http://dx.doi.org/10.1016/j.vaccine.2008.11.031DOI Listing

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