Objective: To study the relationship between intake of nutrients and bone density in the middle-aged and the old people.
Methods: Dietary investigation was conducted and bone densities of lumbar 2-4, tuberositas of femur and the neck of femur were measured in 200 healthy subjects who received physical check-up in our hospital. Subjects were distributed into 6 groups including young or middle-aged, pre-old and old groups of men and women. Comparison was conducted within those groups.
Results: The average intake of protein, carbohydrate and energy per day in old men-group were (71.4 +/- 11.7) g, (294.2 +/- 54.7) g and (2196.9 +/- 311.3) kcal, respectively, which were significantly lower than those in young or middle-aged groups, and the average amounts of protein, carbohydrate and energy intake per day in old men-group were (91.7 +/- 19.5) g, (81.8 +/- 85.2) g and (2716.0 +/- 451.7) kcal, respectively. The average intake of calcium in women-old group was (362.0 +/- 167.1) mg, the lowest in the groups. The incidence of abnormal bone densities of lumbar 2-4, the tuberositas of femur and the neck of femur in old men group was significantly higher than those in young or middle-aged men groups (P < 0.05) and the pre-old men group. There were significantly different incidence rates of abnormal bone densities between the 3 women groups (P < 0.05), especially between young or middle-aged groups and in the old women-group (P < 0.0001). The incidences of abnormal bone density in pre-old men group and old men group were significantly lower than those in-pre-old and old women groups.
Conclusion: The decrease of calcium intake seemed to be one of the factors leading to abnormity of bone density in old women. While the increase of calcium intake served as one of the nutritional factors affecting the bones.
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Arch Osteoporos
January 2025
Beacon Hospital, 1, Jalan 215, Section 51, Off Jalan Templer, 46050, Petaling Jaya, Selangor, Malaysia.
Unlabelled: Osteoporosis, fragility fractures, and bone health optimization share the same pathophysiology, diagnostic tools, risk assessment, and treatments. Grouping them into "Lee's TRIAD" allows surgeons and physicians to collaborate more efficiently, using unified principles and strategies for managing these conditions.
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Calcif Tissue Int
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Department of Bioengineering, Temple University, 1947 N. 12th St, Philadelphia, PA, 19122, USA.
Bone mechanical function is determined by multiple factors, some of which are still being elucidated. Here, we present a multivariate analysis of the role of bone tissue composition in the proximal femur stiffness of cadaver bones (n = 12, age 44-93). Stiffness was assessed by testing under loading conditions simulating a sideways fall onto the hip.
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January 2025
Department of Endocrinology and Metabolism, All India Institute of Medical Sciences Nagpur, Room No 443, OPD Block, 4th Floor, Plot-2, Sector-20, Mihan, Nagpur, 441108, Maharashtra, India.
J Bone Miner Res
January 2025
Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW, Australia.
Rebound bone loss following denosumab discontinuation is an important barrier in the effective long-term treatment of skeletal disorders. This is driven by increased osteoclastic bone resorption following the offset of RANKL inhibition, and sequential osteoclast-directed therapy has been utilised to mitigate this. However, current sequential treatment strategies intervene following the offset of RANKL inhibition and this approach fails to consistently prevent bone loss.
View Article and Find Full Text PDFJ Funct Morphol Kinesiol
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Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo (FORP-USP), Ribeirão Preto 14040-904, Brazil.
Chronic exposure to stress has been considered a risk factor for hypertension, which is also associated with increased bone resorption. This review aimed to investigate the effect of acute and chronic stress, associated with hypertension, on the skeletal system. A comprehensive search was conducted across multiple databases, focusing on peer-reviewed articles published in English.
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