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Thermal-Sensitive Artificial Ionic Skin with Environmental Stability and Self-Healing Property.
ACS Appl Mater Interfaces
January 2025
Key Laboratory of Organic Optoelectronics and Molecular Engineering and Laboratory of Flexible Electronics Technology, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.
Wearable temperature-sensitive electronic skin enables robots to rapidly detect environmental changes and respond intelligently, thereby reducing temperature-related mechanical failures. Additionally, this temperature-sensitive skin can measure and record the temperature of external objects, broadening its potential applications in the medical field. In this study, we designed a thermally sensitive artificial ionic skin using ionic liquids (ILs) as solvents and carbon nanotubes (CNTs) as thermally conductive fillers.
View Article and Find Full Text PDFTargeting antibodies dissociate from drug delivery liposomes during blood circulation.
J Control Release
January 2025
Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark (DTU), Kgs. Lyngby, Denmark. Electronic address:
Despite three decades of intense research, active targeting of liposomes have not been successfully achieved in a clinical setting. A potential explanation is that the clinically used liposomes lose their targeting abilities upon circulation. Here, we investigated if DSPE-PEG anchored antibody-based targeting ligands dissociate from clinically relevant drug delivery liposomes during circulation in mice.
View Article and Find Full Text PDFDissociable effects of perceived control on reward-related neural dynamics under risk and ambiguity.
Neuroimage
January 2025
Department of Psychology, Guangzhou University, Guangzhou, China; Center for Reward and Social Cognition, School of Education, Guangzhou University, Guangzhou, China. Electronic address:
Perceived control plays a crucial role in risk-taking behavior, but its neural effect on reward dynamics in risky and ambiguous decision making remains unclear. Here, we addressed this issue by measuring participants' (N = 40) EEG activity while they were performing a wheel-of-fortune task. Participants either made choices themselves (a high control condition) or followed the computer's choice (a low control condition) under risky or ambiguous decision contexts.
View Article and Find Full Text PDFAdvanced profiling and structural analysis of anencephaly gangliosides by ion mobility tandem mass spectrometry.
Biochimie
January 2025
Department of Condensed Matter, National Institute for Research and Development in Electrochemistry and Condensed Matter, Plautius Andronescu Str. 1, 300224, Timisoara, Romania; Department of Physics, West University of Timisoara, Vasile Parvan, 4, 300223, Romania; Institute for Research, Development and Innovation in Natural and Technical Sciences, Aurel Vlaicu University of Arad, B-dul Revoluţiei 77, 310130, Romania. Electronic address:
Anencephaly, the most severe type of neural tube defects (NTDs) in humans, occurs between the third and fourth gestational weeks (GW), involves the cranial part of the NT and results in the absence of the forebrain and skull. Exposed to amniotic fluid toxicity, neural tissue is degraded and prevented from development. Currently, little is known about the molecular bases of the disease and the possible involvement of glycans.
View Article and Find Full Text PDFThiol-modified hyaluronic acid and hydroxyl radical-induced oxidation synergistically enhance the gelling capacity of ginkgo seed proteins.
Food Chem
January 2025
Department of Food Science and Engineering, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, China. Electronic address:
The objective of this work was to investigate the effect of synthetic thiol-modified hyaluronic acid (HASH) on the gelation properties of ginkgo seed protein isolate (GSPI) under non-oxidizing (NOX) or oxidizing (OX) conditions. Under NOX conditions, HASH mediated the disruption of disulfide bonds, leading to a dose-dependent dissociation of GSPI. Conversely, in OX conditions, hydroxyl radical-induced oxidation facilitated the formation of interprotein disulfide bonds.
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