Mycoplasma pneumoniae (39 strains) was most susceptible to two quinolones, WIN 57273 and sparfloxacin, with MICs for 90% of the strains (MIC90S) of 0.125 and 0.25 micrograms/ml, respectively. It was susceptible to ofloxacin and ciprofloxacin at 2 micrograms/ml and to lomefloxacin and fleroxacin at 4 micrograms/ml. The MIC90 of erythromycin was 0.062 microgram/ml, and that of tetracycline was 1 microgram/ml.
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http://dx.doi.org/10.1128/AAC.35.3.587 | DOI Listing |
Sci Rep
January 2025
Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, China.
Mycoplasma pneumoniae caused lower respiratory tract infection in children and can exacerbate these infections through the production of various inflammatory factors, with chemokines playing a key role. However, the pathogenesis of this infection is complicated and thus has not been thoroughly studied. We clarified that cytokine expression levels were analyzed in both peripheral blood and bronchoalveolar lavage fluid (BALF), and in vitro assays were conducted using THP-1 macrophages.
View Article and Find Full Text PDFCureus
December 2024
Pediatrics, Centro Hospitalar do Oeste, Unidade Caldas da Rainha, Caldas da Rainha, PRT.
An 11-month-old female patient presented to the pediatric emergency room, reporting a high fever and excessive crying. She began taking amoxicillin and clavulanic acid for acute otitis media five days prior. There was no record of trauma, suspected sexual abuse, or other medications involved.
View Article and Find Full Text PDFFront Pediatr
January 2025
Pediatric Respiratory Medicine Department, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Background: infection accounts for a high proportion of community-acquired pneumonia and the incidence rate of severe pneumonia (MPP) has increased year by year. This study investigated the changes in lung diffusion function after infection, compared the lung diffusion and ventilation function of children with mild (MMPP) or severe pneumonia (SMPP) infections, and explored their clinical significance.
Objective: To study the changes in pulmonary ventilation and pulmonary diffusion function in children with MPP, and explore their clinical significance.
Mycoplasma pneumoniae (MP) is one of the pathogens that cause community-acquired pneumonia in children. Atopic diseases are also common in children. However, the impact of atopy on Mycoplasma pneumoniae pneumonia (MPP) in children is still unclear.
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