Reliable methods for the detection of cytomegalovirus (CMV) strain-specific serological responses are lacking. We describe a simple and reliable enzyme-linked immunosorbent assay method developed to detect antibodies against the polymorphic epitopes within the two envelope glycoproteins of CMV, glycoproteins H and B. This assay is useful for the detection of serologic responses to CMV strains and the identification of CMV reinfections.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643547PMC
http://dx.doi.org/10.1128/CVI.00281-08DOI Listing

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