Local excision for rectal carcinoma.

Clin Colorectal Cancer

Department of Surgery, University of California, San Francisco, CA, USA.

Published: November 2008

AI Article Synopsis

  • Local excision offers an alternative to radical proctectomy for rectal cancer, but it's considered a compromise and remains controversial in oncology.
  • Patient selection is crucial, as local excision is typically only recommended for early-stage rectal cancer without nodal metastasis, which can be assessed through clinical exams and imaging techniques.
  • The review discusses the effectiveness of local excision methods, examines outcomes of salvage surgery, and proposes a treatment algorithm for managing rectal cancer with local excision.

Article Abstract

Local excision is an alternative approach to radical proctectomy for rectal cancer, but from an oncologic standpoint, it is a compromise, and its role remains controversial. Careful patient selection is essential because local excision is generally considered only for early rectal cancer with no evidence of nodal metastasis, parameters that can be predicted by clinical examination, and various radiologic modalities with variable accuracy. In this review, we present the literature evaluating the oncologic adequacy of local excision, including transanal endoscopic microsurgery and the results of salvage surgery after local excision. An overview of local excision in the context of perioperative adjuvant therapies is included. Finally, we suggest a treatment algorithm for local excision in rectal cancer.

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Source
http://dx.doi.org/10.3816/CCC.2008.n.050DOI Listing

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