The obtaining and use of genetic data have several particular implications for the rights of the patients and their relatives, and frequently practitioners and researchers face some new conflicts to which law and ethics try to give an answer. Some countries have enacted national laws related to genetic analysis. At the international level a great effort has been done to develop a common regulatory framework taking into account the rights of the patients/subjects of the research and other rights and interests. In the field of genetic analysis, both diagnostic and research purposes frequently go hand in hand. The scientific interest in the use of biological samples as a research tool has increased simultaneously with the knowledge of human genetics. The regulations related to the rights of the patients in the use of biological samples need to be abided.
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http://dx.doi.org/10.1016/j.critrevonc.2008.10.003 | DOI Listing |
Gen Thorac Cardiovasc Surg Cases
January 2025
Department of Cardiovascular Surgery, Osaka General Medical Center, Osaka, 558-8558, Japan.
Background: Left atrial dissection is a rare and occasionally fatal complication of cardiac surgery and is defined as the creation of a false chamber through a tear in the mitral valve annulus extending into the left atrial wall. Some patients are asymptomatic, while others present with various symptoms, such as chest pain, dyspnea, and even cardiac arrest. Although there is no established management for left atrial dissection, surgery should be considered in patients with hemodynamic disruption.
View Article and Find Full Text PDFBMC Cardiovasc Disord
January 2025
ITACA Institute, Universitat Politècnica de València, València, Spain.
Background: Complexity and signal recurrence metrics obtained from body surface potential mapping (BSPM) allow quantifying atrial fibrillation (AF) substrate complexity. This study aims to correlate electrocardiographic imaging (ECGI) detected reentrant patterns with BSPM-calculated signal complexity and recurrence metrics.
Methods: BSPM signals were recorded from 28 AF patients (17 male, 11 women, 62.
J Headache Pain
January 2025
Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina, Italy.
Background: Neuroimaging studies have shown that hypothalamic/thalamic nuclei and other distant brain regions belonging to complex cerebral networks are involved in cluster headache (CH). However, the exact relationship between these areas, which may be dependent or independent, remains to be understood. We investigated differences in resting-state functional connectivity (FC) between brain networks and its relationship with the microstructure of the hypothalamus and thalamus in patients with episodic CH outside attacks and healthy controls (HCs).
View Article and Find Full Text PDFBMC Gastroenterol
January 2025
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Purpose: This study aimed to investigate the efficacy of measuring lymph node size on preoperative CT imaging to predict pathological lymph node metastasis in patients with colon cancer to enhance diagnostic accuracy and improve treatment planning by establishing more reliable assessment methods for lymph node metastasis.
Methods: We retrospectively analyzed 1,056 patients who underwent colorectal resection at our institution between January 2004 and March 2020. From this cohort, 694 patients with resectable colon cancer were included in the study.
BMC Cardiovasc Disord
January 2025
General Practice Ward/International Medical Center Ward, General Practice Medical Center, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, 610041, China.
Background: Catheter-related right atrial thrombus (CRAT) is a severe complication in hemodialysis patients that can lead to catheter dysfunction and pulmonary embolism (PE). However, no standardized treatment strategy currently exists for hemodialysis-related CRAT. This study aims to investigate the efficacy of catheter replacement and antiplatelet therapy in managing hemodialysis CRAT.
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