The effect of deep brain stimulation on the two speech-production subsystems, articulation and phonation, of nine Parkinsonian patients is examined. Production parameters (stop closure voicing; stop closure, VOT, vowel) in fast syllable-repetitions were defined and measured and quantitative, objective metrics of vocal fold function were obtained during vowel production. Speech material was recorded for patients (with and without stimulation) and for a reference group of healthy control speakers. With stimulation, precision of the glottal and supraglottal articulation as well as the phonatory function is reduced for some individuals, whereas for other individuals an improvement is observed. Importantly, the improvement or deterioration is determined not only on the basis of the direction of parameter change but also on the individuals' position relative to the healthy control data. This study also notes differences within an individual in the effects of stimulation on the two speech subsystems. These findings qualify the value of global statements about the effect of neurostimulatory operations on Parkinsonian patients. They also underline the importance of careful consideration of individual differences in the effect of deep brain stimulation on different speech subsystems.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/02699200802394823 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cepstral Changes Following Intensive Voice-Focused Treatment in Parkinson's Disease.
J Voice
January 2025
Teachers College, Columbia University, New York, NY. Electronic address:
Objectives: The purpose of this study was to analyze cepstral changes following intensive voice-focused treatment in Spanish speakers with Parkinson's disease (PD). A secondary aim of the study was to explore the relationship between cepstral values across time and perceptual data across speech subsystems.
Study Design/methods: This study followed a one-group pretest-post test design.
Intensive Speech Therapy for Hypokinetic Dysarthria in Parkinson's Disease: Targeting the Five Subsystems of Speech Production with Clinical and Instrumental Evaluation.
NeuroSci
January 2025
IRCCS San Raffaele Roma, 00163 Rome, Italy.
: Hypokinetic dysarthria is a speech disorder observed in almost 90% of PD patients that can appear at any stage of the disease, usually worsening as the disease progresses. Today, speech therapy intervention in PD is seen as a possible therapeutic option to alleviate and slow down the progression of symptoms. This study aims to investigate the validity of traditional speech therapy in dysarthria with the aim of improving the quality of life of PD patients, by comparing subjective clinical assessment with objective instrumental measures (IOPI and voice analysis).
View Article and Find Full Text PDFCreating the Babel Fish, a tool that helps individuals translate speech between any two languages, requires advanced technological innovation and linguistic expertise. Although conventional speech-to-speech translation systems composed of multiple subsystems performing translation in a cascaded fashion exist, scalable and high-performing unified systems remain underexplored. To address this gap, here we introduce SEAMLESSM4T-Massively Multilingual and Multimodal Machine Translation-a single model that supports speech-to-speech translation (101 to 36 languages), speech-to-text translation (from 101 to 96 languages), text-to-speech translation (from 96 to 36 languages), text-to-text translation (96 languages) and automatic speech recognition (96 languages).
View Article and Find Full Text PDFEvaluation of Acoustic Voice Quality Index in Persian-Speaking Parkinson's Patients Compared to Healthy Controls and Its Association With Disease Severity Based on UPDRS-III and Dysarthria Severity.
J Voice
November 2024
Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Department of Physiotherapy, School of Rehabilitation, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address:
Introduction: Parkinson's patients with dysarthria often suffer from multiple impairments in speech subsystems, including phonation. The Acoustic Voice Quality Index (AVQI) may be considered as a predictor of the onset and severity of Parkinson's disease.
Objective: Investigating the AVQI in Persian-speaking Parkinson's patients compared to healthy controls and its association with disease severity based on Unified Parkinson's Disease Rating Scale-Part III (UPDRS-III) and dysarthria severity.
Did the speech of patients with Myasthenia Gravis decline over 4 years?
Codas
November 2024
Centro de Estudos da Voz - CEV - São Paulo (SP), Brasil.
Purpose: To compare the speech and voice patterns of myasthenia gravis (MG) patients over four years, and correlate the results with clinical aspects of the disease.
Methods: Data was collected for 4 years. The clinical assessment tools included the Quantitative Myasthenia Gravis (QMG) score, the Myasthenia Gravis Foundation of America (MGFA) clinical classification, and the Myasthenia Gravis Quality of Life 15-item Scale (MG-QoL).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!