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The Role of Oxytocin and Vasopressin in People with Borderline Personality Disorder: A Closer Look at Adolescents.
Int J Mol Sci
November 2024
Department of Child and Adolescent Psychiatry, Karol Jonscher Clinical Hospital, Poznan University of Medical Sciences, Szpitalna St. 27/33, 60-572 Poznan, Poland.
Article Synopsis
- Borderline personality disorder (BPD) is a complex medical issue that is gaining more attention among adolescents, but there is still a lack of comprehensive data on it.
- * The causes and ongoing factors of BPD remain unclear, although neuropeptides like oxytocin and vasopressin may play a role in its development.
- * The goal of the research is to gather and evaluate existing studies and ideas about how these neurohormones affect adolescents with borderline personality disorder.*
The pediatric psychopharmacology of autism spectrum disorder: A systematic review - Part II: The future.
Prog Neuropsychopharmacol Biol Psychiatry
October 2024
Department of Public Health and Pediatric Sciences, Section of Child and Adolescent Neuropsychiatry, University of Turin, Turin, Italy.
Part I of this systematic review summarized the state-of-the-art of pediatric psychopharmacology for Autism Spectrum Disorder (ASD), a severe and lifelong neurodevelopmental disorder. The purpose of this Part II follow-up article is to provide a systematic overview of the experimental psychopharmacology of ASD. To this aim, we have first identified in the Clinicaltrials.
View Article and Find Full Text PDFThe small-for-size syndrome in living donor liver transplantation: current management.
Updates Surg
October 2024
Department of Liver Transplantation, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Small-for-size syndrome poses a significant challenge in living donor liver transplantation, with potentially severe consequences including liver failure and death. This review explores the management strategies for SFSS, starting from the pathophysiology of the disease. SFSS arises from insufficient liver mass in the graft and hyperdynamic circulation in cirrhotic recipients, leading to portal hyperperfusion and subsequent liver injury.
View Article and Find Full Text PDFExogenous Opioids and the Human Endocrine System: An Endocrine Society Scientific Statement.
Endocr Rev
November 2024
Section of Endocrinology, Geriatrics and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara 44100, Italy.
The use and misuse of opioids are a growing global problem. Although the effects of these drugs on the human endocrine system have been studied for decades, attention on their related clinical consequences, particularly on the hypothalamic-pituitary system and bone health, has intensified over recent years. This Statement appraises research data related to the impact of opioids on the gonadal and adrenal function.
View Article and Find Full Text PDFClinical characteristics and management of adipsic arginine vasopressin deficiency in children and adolescents with sellar germ cell tumors.
Eur J Pediatr
December 2024
Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, No. 119, South 4 Ring Road West, Beijing, 100071, China.
Article Synopsis
- Adipsic arginine vasopressin deficiency (aAVP-D) is a rare condition that is hard to detect and manage in kids and teens, especially those with certain brain tumors called sellar germ cell tumors (GCTs).
- In a study involving 260 patients, 25 were found to have aAVP-D, which was linked to larger tumors and more health problems like hormonal issues and high levels of certain substances in the blood.
- After treatment, while some symptoms improved, aAVP-D patients still had higher levels of certain substances compared to those without the condition, showing that managing this syndrome remains challenging.
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