Cyclic and linear oligosaccharides constituted with 2-deoxy sugar units are synthesized by an oligomerization reaction involving activated thioglycoside monomers, consisting of a 2-deoxy sugar unit. The oligomerization promoter plays an important role in the formation of either the cyclic- or the linear oligosaccharides. Encapsulation abilities of a 2-deoxy cyclic hexamer with p-nitrophenol, by a (1)H NMR method, showed complexation of the guest molecule with the host molecule.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carres.2008.10.026DOI Listing

Publication Analysis

Top Keywords

linear oligosaccharides
12
2-deoxy cyclic
8
cyclic linear
8
2-deoxy sugar
8
synthesis 2-deoxy
4
oligosaccharides oligomerization
4
oligomerization monomers
4
monomers cyclic
4
oligosaccharides constituted
4
constituted 2-deoxy
4

Similar Publications

Mannan and β-(1→3)-glucan are two polysaccharide markers that are characteristic for a number of fungal pathogens, including , which is the most common cause of invasive mycoses in humans. In this study, we examined epitope specificity of two monoclonal antibodies, CM532 and FG70, which recognize certain oligosaccharide fragments of these fungal polysaccharides. Using a panel of biotinylated oligosaccharides as coating antigens, we found that the CM532 antibody obtained by immunization with the pentamannoside β-Man-(1→2)-β-Man-(1→2)-α-Man-(1→2)-α-Man-(1→2)-α-Man KLH conjugate, selectively recognizes the trisaccharide β-Man-(1→2)-α-Man-(1→2)-α-Man epitope.

View Article and Find Full Text PDF

Profiles of 71 Human Milk Oligosaccharides and Novel Sub-Clusters of Type I Milk: Results from the Ulm SPATZ Health Study.

Nutrients

January 2025

Pediatric Epidemiology, Department of Pediatrics, Medical Faculty, Leipzig University, Liebigstr 20a, Haus 6, 04103 Leipzig, Germany.

Background/objectives: Although approximately 160 human milk oligosaccharides (HMOs) have been identified, current studies on HMO quantitation are limited to the 10-19 most abundant HMOs. We assessed the variations in the relative concentrations of 71 HMO structures over lactation in human milk samples by an advanced liquid chromatography-mass spectrometry approach.

Methods: Samples were collected from 64 mothers at 6 weeks, 6 months, and 12 months of lactation in the Ulm SPATZ Health Study, a German birth cohort.

View Article and Find Full Text PDF

Branching and molecular weight in levan: A detailed analysis of structural variability and enzymatic hydrolysis susceptibility.

Carbohydr Polym

March 2025

Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001 Chamilpa, 62210 Cuernavaca, Morelos, Mexico. Electronic address:

Levan, a β(2 → 6) linked D-fructofuranosyl polymer, is gaining significant attention in basic and applied research. It has been demonstrated that most properties are related to levan molecular weight but also its β(2 → 1) branching degree. In this paper the relationship between levan branching degree, particle size, and molecular weight is reviewed, exploring also how these structural parameters influence levan susceptibility to exo- and endolevanase hydrolysis for levans produced by three recombinants bacterial levansucrases.

View Article and Find Full Text PDF

Dietary fibers (DF) from plant-based foods promote health benefits through their physicochemical properties and fermentation by the gut microbiota, often studied in relation to changes in gut microbiota profile and production of gut microbiota-derived metabolites. Here, we characterized structural motifs (i.e.

View Article and Find Full Text PDF

The development and validation of an accurate, selective, and eco-friendly capillary zone electrophoretic detection (CZE) method has been presented for concurrent measurement of inorganic and organic anions including chloride, sulfate, formic acid, citric acid, acetic acid, phosphate, and glutamic acid in Human Milk Oligosaccharides (HMOs) for the first time. An electrolyte composed of an aqueous solution of benzoic acid, 16.38 mM; l-histidine, 24.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!