Comparison of cefoxitin and oxacillin disk diffusion methods for detection of mecA-mediated resistance in Staphylococcus aureus in a large-scale study.

J Clin Microbiol

Wisconsin State Laboratory of Hygiene, Communicable Disease Division, 465 Henry Mall, Madison, WI 53706, USA.

Published: January 2009

The recommended breakpoints for the cefoxitin disk diffusion test for Staphylococcus aureus were recently modified. In this large-sample study, cefoxitin sensitivity and specificity compared to those of oxacillin were 97.3% and 100%, respectively. This study validated the new cefoxitin breakpoints for the detection of mecA-mediated resistance in S. aureus.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2620872PMC
http://dx.doi.org/10.1128/JCM.01506-08DOI Listing

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