Objective: The purpose of this study was to present an advanced case of rhinophyma and to discuss the pathophysiology, clinical presentation and treatment of this pathology.
Case Report: A 75-year-old patient presented to the ENT out-patient department with a large rhinophyma causing nasal obstruction and eating problems in addition to its aesthetic social burden.
Results: The patient was operated under antibiotic coverage. The operated site was left to heal and later covered with a full-thickness skin graft. During the 5-year postoperative follow-up period, there were no complications, no recurrence of the rhinophyma, and the patient retained a good aesthetic result.
Conclusion: Rhinophyma is the highest of the four grades of rosacea progression. The diagnosis is usually clinical. Surgical treatment is reserved for the advanced nodular forms and is performed under antibiotic coverage in order to prevent the risk of chondrolysis of the nasal cartilages.
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http://dx.doi.org/10.1016/j.aorl.2008.10.001 | DOI Listing |
Curr Drug Saf
January 2025
Qatar University, College of Pharmacy, QU Health, Qatar.
Purpose: The objective of this systematic review is to evaluate the patterns of postsurgical site infections, pre-surgical antibiotics prophylaxis, and related clinical outcomes in the recently published literature.
Methods: This systematic review is registered with PROSPERO registration number CRD42023398963. Several databases and individual journal websites were used to collect data from PubMed/Medline, TRIP, SCOPUS, Elsevier, Springer, ProQuest, and EMBASE.
Cureus
December 2024
Breast Surgery, James Cook University Hospital, Middlesbrough, GBR.
Introduction: Breast surgeries are classified as clean procedures associated with a lower risk of post-operative infections; however, the reported infection rates post-breast surgeries are still significantly high. Surgical site infections (SSIs) are indeed one of the most common and serious complications following breast surgery.
Methodology: A retrospective study assessed the rate of SSIs post-breast reconstructive surgery after the implementation of the infection control protocol at James Cook University Hospital and Friarage Hospital from December 2022 to June 2024.
Plast Surg (Oakv)
February 2025
Division of Allergy and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Antimicrobial prophylaxis is crucial in reducing surgical site infections (SSIs). First-generation cephalosporins are commonly first line, but issues arise when patients report a penicillin allergy. Although up to 10% of Americans report a penicillin allergy, up to 95% are not truly allergic.
View Article and Find Full Text PDFInt J Pharm
January 2025
Department of Radiology, Thomas Jefferson University, 132 S. 10(th) Street, Main 10(th) Floor, Philadelphia, PA 19107, USA.
Post-surgical spinal infection occurs in up to 20% of patients, despite aggressive peri-operative antibiotic treatments. To improve prophylaxis, we have designed and evaluated an ultrasound-activated prophylactic antibiotic release system to combat post-surgical bacterial survival. Polylactic acid (PLA) clips (1 cm) were 3D-printed with an interior reservoir (0.
View Article and Find Full Text PDFChilds Nerv Syst
January 2025
Department of Neurological Surgery, Children's Hospital, Goiânia, Brazil.
Background: Myelomeningocele (MMC) is the most common type of congenital spinal malformation, typically requiring surgical intervention. While prenatal repair is increasingly favored, postnatal repair remains the standard in many settings. This study aims to evaluate the antibiotics prescribed to neonates with MMC and their correlation with central nervous system (CNS) infection rates following postnatal surgical repair.
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