Background: Mongolian spots are congenital hyperpigmented areas of varying size and shape and are usually confluent grayish-blue in color. They are found most frequently in the sacral region and typically disappear during childhood. Occasionally, they persist to adulthood.
Objective: We used Q-switched alexandrite laser treatment for Mongolian spots and examined therapeutic outcomes of 26 Japanese patients who consulted our department.
Materials & Methods: We retrospectively compared 26 Japanese patients before and after treatment.
Results: A good therapeutic outcome was achieved overall, but some adult female patients subsequently developed severe postinflammatory hyperpigmentation. Sacral Mongolian spots were more laser-resistant than extrasacral Mongolian spots.
Conclusion: The outcome correlated with the age of patients at the initiation of treatment; therefore, sacral and extrasacral Mongolian spots should be treated before 20 years of age. To avoid severe postinflammatory hyperpigmentation, the optimal interval between laser treatments and the use of other treatment modalities including Q-switched ruby laser, Q-switched neodymium-doped yttrium aluminium garnet laser, or bleaching creams should be considered. Our results will be of some help in considering the treatment course of patients with Mongolian spots.
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http://dx.doi.org/10.1111/j.1524-4725.2008.34347.x | DOI Listing |
J Cosmet Dermatol
January 2025
Department of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Skin Res Technol
October 2024
Tianjin Children's Hospital/Children's Hospital, Tianjin University, Tianjin, China.
Cureus
May 2024
Dermatopathology, St. Joseph Hospital, Houston, USA.
Dermal melanocytoses are a group of cutaneous disorders characterized by the presence of ectopic melanocytes in the dermis; the most well-known example is the Mongolian spot. Acquired dermal melanocytosis (ADM) is a term used to describe the onset of dermal melanocytosis occurring after its usual age of presentation (i.e.
View Article and Find Full Text PDFInt J Legal Med
September 2024
Institute of Legal Medicine, University Hospital Münster, Münster, Germany.
Cureus
April 2024
Pediatrics, Employee State Insurance Corporation Medical College and Hospital, Sanathnagar, Hyderabad, IND.
Mongolian spots are bluish-grey, irregular, hyperpigmented macules present at birth or that appear in the first few weeks of life. They are classified as atypical if they occur in unusual locations without spontaneous disappearance after infancy; or if new lesions continue to appear beyond early infancy. Although they are generally considered benign, recent studies have shown that atypical Mongolian spots may be associated with inborn errors of metabolism, such as lysosomal storage disorders and neurocristopathies.
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