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Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of the authorisation of a preparation of NCIMB 30005 as technological additive to improve ensiling of fresh material for all animal species. The applicant has provided evidence that the additive currently on the market complies with the existing conditions of authorisation. There was no new evidence that would lead the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) to reconsider its previous conclusions for all animal species, consumers and the environment, for which the additive is considered to remain safe.
View Article and Find Full Text PDFComputational Study Protocol: Leveraging Synthetic Data to Validate a Benchmark Study for Differential Abundance Tests for 16S Microbiome Sequencing Data.
F1000Res
January 2025
Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Baden-Württemberg, Germany.
Background: Synthetic data's utility in benchmark studies depends on its ability to closely mimic real-world conditions and reproduce results obtained from experimental data. Building on Nearing et al.'s study (1), who assessed 14 differential abundance tests using 38 experimental 16S rRNA datasets in a case-control design, we are generating synthetic datasets that mimic the experimental data to verify their findings.
View Article and Find Full Text PDFA case report of unilateral development of painful thyroiditis used as a hallmark of the nervous nature of its pathogenesis.
AME Case Rep
November 2024
Ushakov Thyroid Clinic, Moscow, Russia.
Background: Painful thyroiditis (PT) combines several variants of pathology. The most common is subacute thyroiditis (ST). Despite the prevailing view that the factors underlying the development of ST have an infectious origin, its viral and bacterial pathogeneses remain unclear.
View Article and Find Full Text PDFPrevalence of nonrestorative sleep before and during the COVID-19 pandemic: based on a nationwide cross-sectional survey among Japanese in 2019 and 2022.
Environ Health Prev Med
January 2025
Nara Prefectural Health Research Center, Nara Medical University.
Background: Japanese people sleep less compared to other countries around the world. Using a large nationally representative survey in 2019 and 2022, we investigated whether sleep duration and nonrestorative sleep (NRS) among Japanese people have improved or worsened due to the COVID-19 pandemic.
Methods: Data were drawn from the Comprehensive Survey of Living Conditions, a nationwide cross-sectional sample based on self-administered questionnaires.
Characterizing the relationship between personality dimensions and psychosis-specific clinical characteristics.
Schizophr Res
January 2025
Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Electronic address:
Background: Past studies associating personality with psychosis have been limited by small nonclinical samples and a focus on general symptom burden. This study uses a large clinical sample to examine personality's relationship with psychosis-specific features and compare personality dimensions across clinically and neurobiologically defined categories of psychoses.
Methods: A total of 1352 participants with schizophrenia, schizoaffective disorder, and bipolar with psychosis, as well as 623 healthy controls (HC), drawn from the Bipolar-Schizophrenia Network for Intermediate Phenotypes (BSNIP-2) study, were included.
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