Can fluoxetine alone cause serotonin syndrome in adolescents?

Psychopharmacol Bull

Shiraz University of Medical Sciences, Hafez Hospital, Shiraz, Iran.

Published: March 2012

AI Article Synopsis

Article Abstract

Objective: Serotonin syndrome is usually reported by the use of a combination of drugs. This is a possible case of serotonin syndrome after using Fluoxetine.

Method: This is a case report of serotonin syndrome in an adolescent patient during treatment of depression with the medications. Subsequently, he developed headache, hyperhydrosis (diaphoresis), flushing, shaking, nausea, and vomiting, slurred speech (scanning speech), anxiety, restlessness, agitation, confusion, hallucination, and insomnia. Serotonin syndrome is suggested as one of the most probable diagnosis.

Conclusion: Clinicians treating adolescents should be aware of the potential for serotonin syndrome.

Download full-text PDF

Source

Publication Analysis

Top Keywords

serotonin syndrome
24
syndrome
6
serotonin
5
fluoxetine serotonin
4
syndrome adolescents?
4
adolescents? objective
4
objective serotonin
4
syndrome reported
4
reported combination
4
combination drugs
4

Similar Publications

Rat models of postintracerebral hemorrhage pneumonia induced by nasal inoculation with or intratracheal inoculation with LPS.

Front Immunol

January 2025

State Key Laboratory of Traditional Chinese Medicine Syndrome, Department of Neurology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

Background: A stable and reproducible experimental bacterial pneumonia model postintracerebral hemorrhage (ICH) is necessary to help investigating the pathogenesis and novel treatments of Stroke-associated pneumonia (SAP).

Aim: To establish a Gram-negative bacterial pneumonia-complicating ICH rat model and an acute lung injury (ALI)-complicating ICH rat model.

Methods: We established two standardized models of post-ICH pneumonia by nasal inoculation with () or intratracheal inoculation with lipopolysaccharide (LPS).

View Article and Find Full Text PDF

Challenges in the Management of Severe Serotonin Syndrome: A Case Report.

Cureus

December 2024

Psychiatry and Behavioral Sciences, Kaweah Delta Health Care District, Visalia, USA.

Serotonin syndrome (SS) is a potentially life-threatening condition that can result from excessive serotonergic activity, often due to SSRIs, formally known as selective serotonin reuptake inhibitors. The syndrome and its effects are often secondary to drug-drug interactions or dose-related. This case highlights a 47-year-old female who presents with a history of major depressive disorder, generalized anxiety disorder, and severe alcohol use disorder.

View Article and Find Full Text PDF

Objective: To compare the prevalence of neurodevelopmental and mental health diagnoses in a national sample of youth with sex chromosome trisomies (SCTs) with matched controls.

Methods: Patients in PEDSnet and a diagnosis code mapping to 47,XXY/Klinefelter syndrome (n = 1171), 47,XYY/Double Y syndrome (n = 243), or 47,XXX/Trisomy X syndrome (n = 262) were matched with controls using propensity scores. Generalized estimating equations computed odds ratios (OR) with 95% confidence intervals (CI) for the prevalence of diagnoses within the neurodevelopmental and mental health composites, psychotropic medication prescriptions, and encounters with behavioral health and therapy providers.

View Article and Find Full Text PDF

The impact of borneolum on Citalopram hydrobromide pharmacokinetics and serotonin levels in the hypothalamus of conscious rats.

Nat Prod Res

January 2025

Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Innovation Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Borneolum (BO) is an effectiveness adjuvant in facilitating the transportation of central nervous system drugs to the brain by opening the blood-brain barrier (BBB). Citalopram hydrobromide (CIT-HBr), a widely prescribed serotonin (5-HT) reuptake inhibitor, restricts the efficacy due to the BBB, resulting in slow onset and systemic side effects. Enhancing CIT-HBr's efficacy through BO appears to be a promising approach.

View Article and Find Full Text PDF

Polycystic Ovary Syndrome and Eating Disorders-A Literature Review.

J Clin Med

December 2024

Clinical Department of Gynecologic Surgery and Oncology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects women of reproductive age and is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. PCOS is often associated with hormonal imbalances, metabolic dysfunction and comorbid psychiatric disorders, including eating disorders (EDs). The review identifies key hormonal factors-serotonin, leptin, insulin, ghrelin, kisspeptin and cortisol-and their roles in the pathophysiology of PCOS and associated psychiatric symptoms.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!