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Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides. | LitMetric
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Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides.

Enrique Llobet Catalina March Paloma Giménez José A Bengoechea

Antimicrob Agents Chemother

Program Infection and Immunity, Fundación Caubet-CIMERA Illes Balears, Centro Investigación Biomédica en Red de Enfermedades Respiratorias, Bunyola, Spain.

Published: January 2009

A Klebsiella pneumoniae ompA mutant was more susceptible to antimicrobial peptides (APs) than the wild type. Susceptibility did not result from surface changes other than the absence of OmpA. Our data suggest that OmpA is implicated in the activation of yet-unknown systems dedicated to ameliorating AP cytotoxicity.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612193PMC
http://dx.doi.org/10.1128/AAC.00657-08DOI Listing

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