Comparison of the performances of two in-house rapid methods for antitubercular drug susceptibility testing.

Antimicrob Agents Chemother

Cátedra de Microbiología, Universidad Nacional de Rosario, Argentina.

Published: February 2009

Resistance to rifampin (rifampicin), isoniazid, and streptomycin of 69 Mycobacterium tuberculosis isolates was analyzed by an in-house method based on mycobacteriophage D29 and a colorimetric micromethod. Both methods showed sensitivity and specificity values ranging from 93% to 100%. These simple methods offer an option for drug resistance assessment of M. tuberculosis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630603PMC
http://dx.doi.org/10.1128/AAC.00960-08DOI Listing

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