Objectives: (1) To evaluate the efficacy of the Toxoplasma gondii screening program among Nunavik pregnant women in identifying seroconversions during pregnancy and performing an appropriate follow-up of the seroconverted women and their child; and (2) to evaluate the consequences of congenital Toxoplasma gondii infection.
Participants: Women of child-bearing age and their children born between January 1994 and September 2003.
Setting: Nunavik.
Intervention: Potential cases of infection during pregnancy and of congenital toxoplasmosis were identified on the basis of serologic and hospitalization data. A medical chart revision was then performed. Descriptive statistics regarding the medical follow-up and treatment of suspected cases were compiled.
Outcomes: 31 women who gave birth to 32 children were identified as potential cases. According to the medical charts, 19 women had a potential infection during pregnancy, the others were deemed to have been infected before conception. One woman had a definite infection. This woman and most of the 18 other potentially infected women and their children were treated appropriately. Because of missing data, it was impossible to determine with certainty the final status of two children. A diagnosis of congenital infection was rejected among the other children.
Conclusion: Women with suspected infection and their children were generally well managed by the health care system. No clinical effect of congenital toxoplasmosis was noted during the studied period.
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http://dx.doi.org/10.1007/BF03405249 | DOI Listing |
Pharmaceuticals (Basel)
January 2025
Institute of Physiology, Charité-Universitätsmedizin Berlin, Corporate Member of the Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.
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Methods: The chalcones were prepared according to the Claisen-Schmidt condensation protocol and analyzed.
Pathogens
January 2025
Department of Health Biohazards and Parasitology, Institute of Rural Health, Jaczewskiego 2, 20-090 Lublin, Poland.
The epidemiological situation related to infectious diseases is influenced by many factors. To monitor actual trends in selected zoonoses, a total of 473 serum samples from farmers, forestry workers, and veterinarians were collected for serological examination. Anti- sensu lato (s.
View Article and Find Full Text PDFPathogens
January 2025
Department of Biological and Environmental Sciences, Le Moyne College, Syracuse, NY 13214, USA.
The parasitic protozoa, (), is a model organism for one health because of its wide-ranging impacts on humans, wildlife, and domestic animals. Intermediate hosts, including white-tailed deer (), have been implicated in its maintenance. Prior analysis of seroprevalence in New York State deer focused on rural areas; however, the high density of domestic cats () in urban areas has been implicated in its spread amongst deer.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Pathogen Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
is a globally widespread pathogen of significant veterinary and medical importance, causing abortion or congenital disease in humans and other warm-blooded animals. Nevertheless, the current treatment options are restricted and sometimes result in toxic side effects. Hence, it is essential to discover drugs that demonstrate potent anti- activity.
View Article and Find Full Text PDFMicroorganisms
January 2025
Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA.
is an intracellular protozoan parasite that infects a wide range of vertebrates, including humans. Although cats are the only definitive host, any warm-blooded animal can act as a paratenic host. Throughout the years, this apicomplexan parasite has been studied due to its wide prevalence, zoonotic potential, and host behavioral alterations.
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