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Modelling the human pharyngeal airway: validation of numerical simulations using in vitro experiments. | LitMetric

Modelling the human pharyngeal airway: validation of numerical simulations using in vitro experiments.

Med Biol Eng Comput

INRIA, REO Team, Rocquencourt, BP 105, 78153 Le Chesnay Cedex, France.

Published: January 2009

AI Article Synopsis

  • The study develops a numerical model to predict how airflow can cause collapse in the pharyngeal airway, validating it with lab measurements.
  • It employs theoretical simplifications to reduce computation time while keeping the model clinically relevant by reflecting geometrical and tissue asymmetries, especially under pathological conditions.
  • Results show that the model can accurately predict partial obstruction, with a high prediction accuracy of 4.2% error regarding the deformation in constriction areas.

Article Abstract

In the presented study, a numerical model which predicts the flow-induced collapse within the pharyngeal airway is validated using in vitro measurements. Theoretical simplifications were considered to limit the computation time. Systematic comparisons between simulations and measurements were performed on an in vitro replica, which reflects asymmetries of the geometry and of the tissue properties at the base of the tongue and in pathological conditions (strong initial obstruction). First, partial obstruction is observed and predicted. Moreover, the prediction accuracy of the numerical model is of 4.2% concerning the deformation (mean quadratic error on the constriction area). It shows the ability of the assumptions and method to predict accurately and quickly a fluid-structure interaction.

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Source
http://dx.doi.org/10.1007/s11517-008-0412-1DOI Listing

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