The rifamycin rifalazil (RFZ), and derivatives (NCEs) were efficacious in a mouse model of Helicobacter pylori colonization. Select NCEs were more active in vitro and showed greater efficacy than RFZ. A systemic component contributes to efficacy.

Download full-text PDF

Source
http://dx.doi.org/10.1038/ja.2008.64DOI Listing

Publication Analysis

Top Keywords

mouse model
8
pylori colonization
8
rifalazil derivative
4
derivative compounds
4
compounds potent
4
potent efficacy
4
efficacy mouse
4
model pylori
4
colonization rifamycin
4
rifamycin rifalazil
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!