[Impact of preoperative decompression of bile ducts on results of surgical treatment in patients with pancreatic cancer complicated with jaundice].

The aim of this research was to study the efficiency of preoperative decompression of bile ducts in patients with pancreatic cancer, complicated with obstructive jaundice. In a retrospective study short-term results of surgical treatment of patients with preoperative drainage and patients without drainage of bile ducts were compared. The operative characteristics such as median operative time, intraoperative blood transfusion and early postoperative results such as mortality, morbidity, postoperative complications of 300 patients: 160 patients with preoperative drainage and 140 patients without drainage of bile ducts were compared. It was found that the drainage and non-drainage groups did not differ according to age, gender, preoperative condition and character of pathology. The non-drainage group demonstrated more favorable results for postoperative morbidity (0,002), re-laparotomy (0,001), median operation time (p<0,05), postoperative pancreatitis (0,018), median hospital stay (p=0,03) and wound infection (0,032) . Mortality rate in drainage group was 2,9% (4 patients), in non-drainage group was 2,9% (4 patients). The result of our study demonstrated that pre-operative drainage of bile duct in patients with periampulary malignomas lead to increased early postoperative septic complications and therefore is not enough effective procedure.