Flapless immediate implant surgery has been proposed as a means of reducing the surgical trauma to soft tissue and maintaining natural gingival anatomy. The aesthetic outcome in such cases may, however, be jeopardized when localized horizontal and vertical deficiencies occur. In order to correct such deficiencies, a novel flap design was developed that protected the soft tissue that had the most significant impact on the patient's appearance. This aesthetic buccal flap (ABF) was created coronally so that the supraosseous soft tissue remained undisturbed and allowed the use of guided bone regeneration techniques to correct apical dehiscences. The likelihood of obtaining an optimal aesthetic result was, therefore, enhanced.
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Sci Rep
January 2025
Department of Orthopedics, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, 305 East Zhongshan Road, Nanjing, 210002, Jiangsu, China.
Extraskeletal osteosarcoma (ESOS) is a very rare malignant tumor. This study aimed to provide more evidence about the natural history and clinical features of ESOS, and clarify the impact of chemotherapy (CT) and radiotherapy (RT) on patient survival and postoperative recurrence for the sake of gaining a better understanding about the disease. Patient/tumor characteristics, recurrence, treatment, and follow-up durations were collected by searching studies in PubMed, Web of Science, Ovid, Elsevier, SpringerLink, Chinese National Knowledge Infrastructure (CNKI), and WAN FANG Data before June 30, 2023.
View Article and Find Full Text PDFBMC Public Health
January 2025
One Health Lesson Administrative Intern, Addis Ababa, Ethiopia.
Background: According to the World Health Organization (WHO), there were 1.19 million road traffic accident (RTA)-related deaths in 2021, with a significantly higher death rate in developing countries than in developed countries.
Objective: To assess the distribution of causes of death and associated organ injuries in RTA-related fatalities.
Int J Biol Macromol
January 2025
School of Materials and Mineral Resources Engineering, Engineering Campus, Universiti Sains Malaysia, 14300 Nibong Tebal, Penang, Malaysia. Electronic address:
Guided tissue regeneration (GTR) and guided bone regeneration (GBR) are two common dental regenerative procedures used to repair periodontal defects caused by periodontitis. In both procedures, a barrier membrane is placed at the interface between the soft tissue and the periodontal defect, serving to impede the infiltration of soft tissue while creating a secluded space for periodontal regeneration. Recently, barrier membranes based on chitosan (CS) have emerged as a promising avenue for these applications.
View Article and Find Full Text PDFGene
January 2025
Department of Orthopedics, The Second Affiliated Hospital of Guangxi Medical University, No. 166 East University Road, Nanning 530005, Guangxi, PR China. Electronic address:
Emerging evidence suggests that circular RNAs (circRNAs), a class of non-coding RNAs, play a critical role in the progression of several cancers, including osteosarcoma (OS). In this study, we focused on a specific circRNA, hsa_circ_0002005, derived from the mesoderm-induced early response 1 family member 2 (MIER2) gene. We determined the expression levels of hsa_circ_0002005 in OS samples through the use of real-time quantitative polymerase chain reaction (RT-qPCR).
View Article and Find Full Text PDFIndian J Med Microbiol
January 2025
Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India; Central Research Lab, Sri Venkateswaraa Medical College Hospital and Research Centre, Ariyur , Puducherry, India. Electronic address:
Background: Vancomycin has been the preferred treatment for MRSA infections. However, newer drugs are necessary due to the increasing prevalence of MRSA isolates that are less susceptible to vancomycin. Levonadifloxacin its a prodrug alalevonadifloxacin, novel quinolones with broad spectrum anti-MRSA activity.
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