Juvenile xanthogranulomatosis (JXG) is an uncommon histiocytic disease that is usually limited to the skin. Here we describe an infant with systemic JXG including a central nervous system (CNS) lesion. He was initially treated with prednisolone and vinblastine but developed an idiosyncratic reaction to prednisolone that was discontinued. The lesion then failed to respond to vinblastine monotherapy. Treatment with cladribine (2-chlorodeoxyadenosine) was subsequently successful with radiological resolution of the CNS lesion.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/pbc.21830 | DOI Listing |
Publication Analysis
Top Keywords
central nervous
8
nervous system
8
juvenile xanthogranulomatosis
8
cns lesion
8
successful treatment
4
treatment central
4
system juvenile
4
xanthogranulomatosis cladribine
4
cladribine juvenile
4
xanthogranulomatosis jxg
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!