Necrolytic acral erythema: successful treatment with topical tacrolimus ointment.

Int J Dermatol

Department of Dermatology, Niazi Medical Complex Hospital, Club Road, Sargodha, Pakistan.

Published: October 2008

Necrolytic acral erythema is a relatively recently described psoriasis-like skin eruption seen in people infected with hepatitis C virus. Hepatitis C virus infection is endemic in many parts of the world with a steady increase of incidence in Pakistan. Recognition of this disorder is crucial to an early treatment of the underlying liver disease. Herein, we report the first case of necrolytic acral erythema from Asia and also describe good therapeutic response to topical tacrolimus ointment.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-4632.2008.03710.xDOI Listing

Publication Analysis

Top Keywords

necrolytic acral
12
acral erythema
12
topical tacrolimus
8
tacrolimus ointment
8
hepatitis virus
8
erythema successful
4
successful treatment
4
treatment topical
4
ointment necrolytic
4
erythema described
4

Similar Publications

Article Synopsis
  • * A case study discusses a 66-year-old patient who, after having gastric bypass surgery, developed NAE due to a poor diet limited to just mushroom soup for three months, without any history of hepatitis C.
  • * The patient was treated with zinc replacement after other treatments failed, and showed significant improvement at follow-up, highlighting how NAE can occur from nutritional deficiencies outside of known viral infections like HCV.
View Article and Find Full Text PDF
Article Synopsis
  • Hepatitis C virus (HCV) is a significant cause of serious liver diseases, such as chronic hepatitis and liver cirrhosis, as well as hepatocellular carcinoma.
  • Chronic HCV infection is also linked to various extrahepatic conditions that can result in serious health issues, including cryoglobulinemia, autoimmune diseases, and cardiovascular problems.
  • Understanding these extrahepatic manifestations is crucial for early diagnosis and effective anti-viral treatment, which can help reduce long-term complications related to chronic HCV infection.
View Article and Find Full Text PDF
Article Synopsis
  • Necrolytic acral erythema (NAE) is a rare skin condition often linked to hepatitis C virus (HCV), characterized by thick, scaly patches on the arms and legs.
  • Some studies have documented occurrences of NAE without any HCV infection, indicating it may have other causes.
  • This case study highlights a female patient diagnosed with NAE who also has hypothyroidism, but does not have HCV.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!