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Spatial-Structural Mechanisms of Racialized Disparities in Overdose Mortality: A Spatiotemporal Analysis.
J Racial Ethn Health Disparities
January 2025
Department of Pharmacology & Toxicology, Medical College of Wisconsin, Milwaukee, WI, USA.
Efforts to understand and respond to the opioid crisis have focused on overdose fatalities. Overdose mortality rates (ratios of overdoses resulting in death) are rarely examined though they are important indicators of harm reduction effectiveness. Factors that vary across urban communities likely determine which community members are receiving the resources needed to reduce fatal overdose risk.
View Article and Find Full Text PDFDisability Benefit and Gambling Disorder: A Longitudinal Study Based on National Registry Data.
J Gambl Stud
January 2025
Department of Psychosocial Science, University of Bergen, P.O. box 7807, Bergen, 5020, Norway.
Rates of gambling disorder (GD) have been found to be higher among people receiving disability benefit, but few studies have investigated whether receiving disability benefit prospectively actually increases the risk of GD. The present study investigated whether those with a disability benefit had an increased risk of developing GD using a case-control design. The study sample was retrieved from the Norwegian Patient Registry (NPR, N = 5,131) and consisted of all adults in Norway (18 years and older) who had received a GD diagnosis (F63.
View Article and Find Full Text PDFAFB1 consolidates HBV harm to induce liver injury and carcinogenic risk by inactivating FTCD-AS1-PXR-MASP1 axis.
Toxicology
January 2025
Department of Pharmacology, Shantou University Medical College, Shantou 515041, China. Electronic address:
Aflatoxin B1 (AFB1) has been reported to synergize with hepatitis B virus (HBV) to induce development of hepatocellular carcinoma (HCC). Precise daily exposure to AFB1 and its contribution to liver injury have not been quantified and have even been disregarded due to lack of convenient detection, and the strong species specificity of HBV infection has restricted research on their synergistic harm. Hence, our objective was to investigate the molecular mechanisms by which AFB1 exacerbates HBV-related injury.
View Article and Find Full Text PDFRisk characterisation of chemicals of emerging concern in real-life water reuse applications.
Environ Int
January 2025
Institute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, The Netherlands.
Water reuse is a viable option to address temporal or structural water shortages. However, the ubiquitous presence of chemicals of emerging concern (CECs) in natural systems, especially the aquatic environment, represents a significant obstacle to water reuse and the receiving environment. Therefore, an extensive literature review was performed to identify current water reuse practices at field scale, reported types and levels of CECs and their associated risks for human and environmental health.
View Article and Find Full Text PDFBad year econometrics: Agent-based modeling of risk management strategies under varying regimes of environmental change.
Sci Adv
January 2025
Department of Archaeology and Heritage Studies, Aarhus University, Aarhus, Denmark.
Resilience-the ability of socio-ecological systems to withstand and recover from shocks-is a key research and policy focus. Definitions of resilience differ between disciplines, however, and the term remains inadequately operationalized. Resilience is the outcome of variable behavioral decisions, yet the process itself and the strategies behind it have rarely been addressed quantitatively.
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