Introduction And Aims: Attention deficit hyperactivity disorder (ADHD) is currently of great interest to the public and the diagnostic process, evaluation of the follow-up and therapeutic strategies in these patients are the subject of a fierce debate. In this study we assess compliance with the ADHD diagnostic and therapeutic guidelines in Spain, in relation to the American Academy of Pediatrics (AAP) guidelines, and it is measured using the Achievable Benchmarks of Care (ABC) technique.
Subjects And Methods: The study involved 215 specialists, 138 child and youth psychiatrists, and 77 neuropaediatricians. Questions were selected to elicit responses on compliance with the AAP diagnostic (1 to 5) and therapeutic (1 to 5) guidelines. The ABC technique, developed at the University of Alabama, Birmingham, USA, was applied for the analysis.
Results: The degree of compliance with the diagnostic guidelines was: guideline 2, 63.1% (ABC 100%), guidelines 3 and 4, 65.8% (ABC 100%) and guideline 5, 87% (ABC 100%); and in the treatment guidelines: guideline 2, 87.1% (ABC 100%) and guideline 3, 71.2% (ABC 100%).
Conclusions: Compliance with the AAP guidelines for treating patients with ADHD is higher than observance of the diagnostic guidelines. In 10% of the best centres (ABC) compliance reaches 100% of all the guidelines, a high degree of adherence to the US guidelines, although compliance with them is not mandatory in our clinical area.
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Front Neurol
January 2025
Neurosciences and Clinical Department, Centro Universitário ABC, Santo André, Brazil.
Introduction: Differential diagnosis of rare idiopathic inflammatory myopathies (IIM) is mainly based on clinical aspects, muscle biopsy analysis, and auxiliary assays that determine myositis-specific and associated autoantibodies (MSA and MAA). While MSAs are considered specific for their respective IIM subclass, MAAs can be present in more than one subclass and in other conditions. This study compares results of a multispecific line blot assay with the final diagnosis of IIM patients based on clinical features and muscle biopsy to draw conclusions for the test's applicability in the diagnostic workflow.
View Article and Find Full Text PDFJ Thorac Dis
December 2024
Department of Cardiothoracic Surgery, Instituto Nacional de Cardiologia Ignacio Chávez, Mexico City, Mexico.
Background: Takayasu arteritis (TA) affects medium and large caliber arteries causing stenosis, occlusion, or aneurysms. It has great predilection for the aortic arch, subclavian and extracranial arteries. The global prevalence is of 1% to 2% per million inhabitants, which varies by geographical region.
View Article and Find Full Text PDFJ Hum Reprod Sci
December 2024
Department of Endocrinology, M.K.C.G Medical College, Berhampur, Odisha, India.
Background: Polycystic ovary syndrome (PCOS) presents a complex diagnostic challenge due to its heterogeneous nature.
Aim: This study aimed to examine the diagnostic utility of various hormones across different PCOS phenotypes.
Settings And Design: This cross-sectional study was carried out in 187 newly diagnosed PCOS women (18-40 years) attending the outdoor clinics of the department of endocrinology and obstetrics and gynaecology of a tertiary care centre in India.
Front Neurol
January 2025
Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China.
Objectives: This study aimed to assess the psychometric properties of the Chinese version of the Stay Independent Questionnaire (C-SIQ) in evaluating individuals with stroke.
Design: The study adopted a cross-sectional design.
Setting: The research was conducted at a university-based neurorehabilitation center.
Bioelectrochemistry
January 2025
Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, São Paulo 09210-580, Brazil. Electronic address:
Owing to fast SARS-CoV-2 mutations, biosensors employing antibodies as biorecognition elements have presented problems with sensitivity and accuracy. To face these challenges, antibodies can be replaced with the human angiotensin converting enzyme 2 (ACE-2), where it has been shown that the affinity between ACE-2 and the receptor binding domain (RBD) increases with the emergence of new variants. Herein, we report on Ni-doped ZnO nanorod electrochemical biosensors employing an ACE-2 peptide (IEEQAKTFLDKFNHEAEDLFYQS-NH) as a biorecognition element for detecting Spike (S) Wild-Type (WT) protein.
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