AI Article Synopsis
- The study aimed to explore how the culture time of chorionic villus samples affects their weight.
- After analyzing 1,442 samples, it was found that as culture time increased, the weight of the villi decreased, with a notable correlation (r = -0.258, p < 0.01).
- Although there was a significant correlation between culture time and villus weight, the difference in culture time was only 1-2 days across various weight groups, suggesting the findings lack clinical relevance.
Article Abstract
Objective: It was the aim of our study to investigate the association between culture time and weight of villi obtained by transabdominal chorionic villus sampling (CVS).
Methods: We analyzed 1,442 villus samples.
Results: The gestational age at sampling ranged from 10 to 14 weeks. The weight of villi in these samples ranged from 1 to 80 mg (median 10 mg, interquatile range 7-12 mg). The culture time ranged from 5 to 24 days. Culture time was significantly and inversely correlated with the weight of villi obtained (r = -0.258, p < 0.01). Time was significantly longer when 5 mg or less of villi was obtained but the difference was only up to 2 days.
Conclusions: Because the difference in culture time for different groups of villus samples was within 1-2 days, this relationship is statistically significant but has no clinical significance.
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| http://dx.doi.org/10.1159/000167876 | DOI Listing |
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