A unifying nitrososynthase involved in nitrosugar biosynthesis.

J Am Chem Soc

Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, USA.

Published: November 2008

Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris. The purified enzymes play the same role, the double-oxidation of TDP-evernosamine to TDP-evernitrosose in the everninomycin and rubradirin pathways, respectively.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661260PMC
http://dx.doi.org/10.1021/ja8051415DOI Listing

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Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris.

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