Aim: We represent variation of bilio-digestive stomy with "lost" protecting drainage during conventional palliative procedure of nonresectable tumors of periampullary region.
Materials And Methods: During the period 01.01.2008 -31.05.2008 in the Clinic of general and liver-pancreatic surgery-"Aleksandrovska" Hospital, Sofia, we applied modified technique for internal bilio-digestive prosthetic drain with "lost" drainage, protecting choledocho-duodenostomy in 12 patients with nonresectable tumors of periampullary region. Eight of them are males and 4--females, with age between 60-82 (average 64,5). In 8 patients we found nonresectable malignancy of the head of pancreas and in 4 nonresectable malignancy of distal part of the common bile duct.
Results: We follow the early postoperative results and postoperative period during tree months. We did not have insufficiency of the choledocho-duodenostomy and that afford early discharge of the patients. At the end of third month we haven't observed jaundice or other complications cause of obstruction of protecting drainage.
Conclusion: We consider that the technique is useful and appropriate when doing choledocho-duodenostomy cause of nonresectable periampullary neoplasms. The using of this technique don't increase the postoperative morbidity and improve early postoperative results.
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Ann Hepatobiliary Pancreat Surg
January 2025
Department of Hepato-Pancreato-Biliary Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.
Backgrounds/aims: Irreversible electroporation (IRE) may have a potential application as either a "back-up therapy" or for margin accentuation during trial dissection of locally advanced pancreatic cancer (LAPC). The aim of this report was to describe our experience with IRE in terms of its potential applications mentioned above.
Methods: A clinical policy to use IRE in LAPC patients undergoing exploratory surgery after neoadjuvant therapy (NAT) was initiated in 2017.
Nihon Shokakibyo Gakkai Zasshi
January 2025
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo.
J Clin Med
December 2024
Department of Radiotherapy and Radiation Oncology, Faculty of Medicine, University of Augsburg, 86156 Augsburg, Germany.
: To analyze the results of interstitial (IRT) high-dose-rate (HDR) brachytherapy (BT) in the primary treatment of patients with unresectable superior sulcus tumors (SST) combined with external beam radiotherapy (EBRT). : Between 2013 and 2023, seven patients with unresectable SST were treated with combined BT and EBRT with or without concomitant chemotherapy. The patients' median age was 64 years (range, 49-79 years) and median tumor volume was 146.
View Article and Find Full Text PDFJ Hepatobiliary Pancreat Sci
January 2025
Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
After the World Health Organization established a precise definition of mucinous cystic neoplasm (MCN) in 2000, based on the presence of ovarian-type stroma, its clinical features became more apparent. Surgery for MCN, which primarily affects middle-aged women with long life expectancies, is likely to negatively impact the patient's quality of life. Although recent studies have reported a low proportion of advanced neoplasia among resected MCN (≤15%), many clinicians still recommend surgery for patients with presumed MCN without considering risk stratification for advanced neoplasia.
View Article and Find Full Text PDFClin Transl Oncol
December 2024
HM CIOCC MADRID (Centro Integral Oncológico Clara Campal), Laboratorio de Innovación en Oncología, Instituto de Investigación Sanitaria HM Hospitales, Oña Street 10, 28050, Madrid, Spain.
Background: Granulosa cell ovarian tumors (GCTs) are a rare neoplasia characterized by a pathognomonic mutation in the FOXL2 gene. In vitro studies have demonstrated an overactivation of hormone activity due to this alteration. Thus, we aimed to determine the activity of orteronel, a CYP17 inhibitor, in advanced disease.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!