The dropout rate in the Finnish military service has increased during the past two decades. At the same time, the physical fitness level of young Finnish males has decreased, possibly leading to overtraining in new conscripts. The purpose of the present study was to examine whether body composition would influence neuromuscular function during the 8-week basic training (BT) period. Eighteen healthy male subjects (19 +/- 1 years) were divided into three different groups according to their body fat %. Group 1 (<10%), group 2 (10-13%) and group 3 (>13%). The soleus H-reflex response was measured in the standing position. In the seated position (knee 160 degrees and hip 110 degrees), the V-wave response was measured during maximal voluntary contraction, and the single twitch response was measured in passive conditions. In body composition (fat-free mass and fat mass) was observed small but not significant changes during 8-week period. H-reflex activity increased in groups 2 (10.9% not significant [ns]) and 3 (2.8% ns) but decreased in group 1 (-34.8%, p < 0.05) during the 8-week period. V-wave values decreased in all groups, and the biggest decrement was observed in group 2 (-34.7%, p < 0.05), whereas in group 1 and group 3 no significance was observed. For each group the single twitch torque (G1 ns, G2 and G3 p < 0.05) increased during the 8-week period. The major finding of the study was that the BT period did not cause overtraining in conscripts. Increased activity of the H-reflex and single twitch torque supports this finding. V-wave activity was decreased in all groups, which may also indicate that the training did not stimulate neural activity. In general, the observed changes in neuromuscular system supports the main finding.
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http://dx.doi.org/10.1519/JSC.0b013e3181854dc1 | DOI Listing |
J Med Internet Res
January 2025
Department of Rehabilitation Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Sarcopenia is closely associated with a poor quality of life and mortality, and its prevention and treatment represent a critical area of research. Resistance training is an effective treatment for older adults with sarcopenia. However, they often face challenges when receiving traditional rehabilitation treatments at hospitals.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Nutritional Physiology, National Institute of Medical and Nutritional Sciences "Salvador Zubirán", Mexico City, Mexico.
Childhood obesity increases the risk of developing metabolic diseases in adulthood, since environmental stimuli during critical windows of development can impact on adult metabolic health. Studies demonstrating the effect of prepubertal diet on adult metabolic disease risk are still limited. We hypothesized that a prepubertal control diet (CD) protects the adult metabolic phenotype from diet-induced obesity (DIO), while a high-fat diet (HFD) would predispose to adult metabolic alterations.
View Article and Find Full Text PDFPLoS One
January 2025
Laboratory of Ecology and Zoology of Vertebrates, Institute of Biological Science, Federal University of Pará, Belém, Pará, Brazil.
Bauxite mining has been caused severe changes in the natural ecosystems of the Amazon, but the restoration of these areas is mandatory by federal law in Brazil. The recolonization of fauna is crucial to establishing the ecological functions of recovering forests, and the small nonflying mammals can stand out in this process. Assessing taxonomic and functional diversity parameters, we demonstrated that in the early stages of forest recovery post-bauxite mining, between 6 and 11 years, it is possible to restore approximately 45% of the richness of small non-flying mammal species from the original habitats, that in this case were altered Primary Forests.
View Article and Find Full Text PDFPLoS One
January 2025
Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, Arizona, United States of America.
Translational validity of mouse models of Alzheimer's disease (AD) is variable. Because change in weight is a well-documented precursor of AD, we investigated whether diversity of human AD risk weight phenotypes was evident in a longitudinally characterized cohort of 1,196 female and male humanized APOE (hAPOE) mice, monitored up to 28 months of age which is equivalent to 81 human years. Autoregressive Hidden Markov Model (AHMM) incorporating age, sex, and APOE genotype was employed to identify emergent weight trajectories and phenotypes.
View Article and Find Full Text PDFPLoS Biol
January 2025
Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.
The unique architecture of the liver consists of hepatic lobules, dividing the hepatic features of metabolism into 2 distinct zones, namely the pericentral and periportal zones, the spatial characteristics of which are broadly defined as metabolic zonation. R-spondin3 (Rspo3), a bioactive protein promoting the Wnt signaling pathway, regulates metabolic features especially around hepatic central veins. However, the functional impact of hepatic metabolic zonation, regulated by the Rspo3/Wnt signaling pathway, on whole-body metabolism homeostasis remains poorly understood.
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