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Postoperative hemorrhages (POHs) after pituitary adenoma surgery can have devastating consequences for patients. Many patients take acetylsalicylic acid (ASA) for the primary or secondary prevention of cardiovascular or stroke events. However, the impact of continued low-dose ASA use on the risk of postoperative hemorrhage and the frequency of thromboembolic events after discontinuing ASA in these patients remain poorly understood.

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The influence of Acrylate Styrene Acrylonitrile (ASA) and ASA/nanosilica (ASA/Si) additives was investigated by using a dynamic shear rheometer (DSR). Firstly, an ASA polymer was blended with the virgin asphalt binder at two different concentrations (3% ASA and 5% ASA). After observing that 5% ASA was the optimum concentration for modification, nanosilica particles were further incorporated into the 5% ASA-modified asphalt binder with two different percentages (5% ASA 3%Si; 5% ASA 5%Si).

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Background/objectives: Patients with gliomas show an increased risk of spontaneous hemorrhages throughout the disease. Simultaneously, the number of patients taking acetylsalicylic acid (ASA) for primary and secondary prophylaxis is rising in daily clinical practice, and interrupting ASA intake before elective or emergency intracranial surgery is not always feasible. This study aims to evaluate the risks associated with continuing ASA use perioperatively while focusing on hemorrhage and potential thromboembolic events that may arise from discontinuing ASA, particularly in multimorbid patients undergoing glioma surgery.

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Learning curve and long-term outcomes of minimally invasive correction and fusion for adolescent idiopathic scoliosis.

Spine Deform

November 2024

Dell Medical School, The University of Texas, Ascension Texas Spine and Scoliosis, 1004 West 32nd Street, Suite 200, Austin, TX, 78705, USA.

Study Design: Retrospective analysis.

Objective: This study sought to report the long-term outcomes of patients that underwent minimally invasive surgery (MIS) correction for Adolescent Idiopathic Scoliosis (AIS) in terms of radiographic, clinical, and patient-reported outcomes. Furthermore, we examined the learning curve of MIS technique over the course of 13 years.

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Article Synopsis
  • The study aimed to assess the Modified Frailty Index (MFI-5) as a tool for predicting preoperative risks in patients undergoing video-assisted thoracoscopic surgery (VATS) who are classified under the same ASA class.
  • It analyzed data from 69,145 patients using the American College of Surgeons' National Surgical Quality Improvement Program (NSQIP) database collected between 2008 and 2021 across various hospitals.
  • The results indicated that while the ASA classification alone correlated well with complications such as unplanned reintubation and prolonged ventilator dependence, combining it with MFI-5 provided an even stronger predictive capability, especially for patients classified as ASA class 3.
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