Objective: To evaluate the psychosocial well-being of 9-18-year-old IVF children. IVF alters fetal programming, with consequences for physical functioning. This also may apply to behavior. Behavior and socioemotional functioning of children born after IVF and spontaneously from parents with former fertility problems were studied, to control for parental factors and investigate the role of IVF on the children's functioning.
Design: Child Behavior CheckList (CBCL) and Teacher Report Form (TRF) reports of 139 IVF and 143 control children.
Setting: VU University Medical Center, Amsterdam.
Subject(s): Children's age ranged from 9 to 18 years; mean age 13.60 (+/-2.12) years in IVF and 13.51 (+/-2.11) years in controls.
Main Outcome Measure(s): Child's behavior and socioemotional functioning reported by parents (CBCL) and teachers (TRF).
Result(s): The CBCL and TRF mean scores were within the normal range. Scores of IVF parents versus controls were lower on the total problems scale, externalizing scale and syndrome scales thought problems, attention problems, aggressive and rule-breaking behavior. Less IVF children had scores in the borderline/clinical range on these scales. On the TRF, a tendency was found for lower scores on the externalizing scale in IVF children compared with controls. More IVF children scored in the borderline/clinical range on the syndrome scale withdrawn/depressed behavior.
Conclusion(s): Overall, behavior, and socioemotional functioning of 9-18-year-old IVF children is normal. The reduced behavior of externalizing nature reported by the parents, and teacher ratings of more withdrawn/depressed behavior need further study.
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http://dx.doi.org/10.1016/j.fertnstert.2008.09.026 | DOI Listing |
Front Endocrinol (Lausanne)
December 2024
Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China.
Purpose: Infertility is affecting more and more couples of appropriate age. Hysteroscopy (HSC) has certain effects on the uncompleted pregnancy and live birth caused by uterine microenvironment. Based on the evidence, this paper systematically evaluates the effectiveness and safety of HSC intervention on the fertility outcome of female infertility.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Techniques for sperm cryopreservation have exhibited their potential in male fertility preservation. The use of frozen-thawed sperm in fertilization (IVF) cycles is widespread today. However, many studies reported that cryopreservation might have adverse effects on sperm DNA integrity, motility, and fertilization, probably due to cold shock, intra- and extracellular ice crystals, and excess reactive oxygen species (ROS).
View Article and Find Full Text PDFJ Assist Reprod Genet
December 2024
State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, 250012, China.
Purpose: This study aims to explore the impact of a woman's previous cesarean delivery (CD) on pregnancy and neonatal outcomes for subsequent in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) and single frozen-thawed embryo transfer (FET), compared with vaginal delivery (VD).
Methods: This was a retrospective cohort study that included a total of 5817 patients who desired to transfer a single vitrified-thawed blastocyst from the same oocyte retrieval cycle as their last live birth between January 2011 and January 2021 at a single reproductive medicine center. Patients with a single previous CD were classified in the CD group, while those with a single VD were assigned to the VD group.
Hum Reprod
December 2024
Assisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, China.
Study Question: Are live birth rates (LBRs) per woman following flexible progestin-primed ovarian stimulation (fPPOS) treatment non-inferior to LBRs per woman following the conventional GnRH-antagonist protocol in expected suboptimal responders undergoing freeze-all cycles in assisted reproduction treatment?
Summary Answer: In women expected to have a suboptimal response, the 12-month likelihood of live birth with the fPPOS treatment did not achieve the non-inferiority criteria when compared to the standard GnRH antagonist protocol for IVF/ICSI treatment with a freeze-all strategy.
What Is Known Already: The standard PPOS protocol is effective for ovarian stimulation, where medroxyprogesterone acetate (MPA) is conventionally administered in the early follicular phase for ovulatory suppression. Recent retrospective cohort studies on donor cycles have shown the potential to prevent premature ovulation and maintain oocyte yields by delaying the administration of MPA until the midcycle (referred to as fPPOS), similar to GnRH antagonist injections.
Cureus
November 2024
Department of Obstetrics and Gynecology, St. Luke's International Hospital, Tokyo, JPN.
Objective: This study aimed to evaluate the change in the patient's background and attitude toward infertility treatment both before and after the initiation of insurance coverage and to explore future issues from the patients' perspectives.
Materials And Methods: A cross-sectional survey was conducted in a fertility clinic in Japan from February to June 2022. An original questionnaire was given for two groups of new patients at a fertility clinic on their first visit: before fertility treatment insurance coverage started (Before-coverage) and after fertility treatment insurance coverage started (After-coverage).
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