Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671494 | PMC |
| http://dx.doi.org/10.1523/JNEUROSCI.0002-08.2008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Comparison of the Next Eigenvalue Sufficiency Test to Other Stopping Rules for the Number of Factors in Factor Analysis.
Educ Psychol Meas
January 2025
Université TÉLUQ, Montréal, Québec, Canada.
A plethora of techniques exist to determine the number of factors to retain in exploratory factor analysis. A recent and promising technique is the Next Eigenvalue Sufficiency Test (NEST), but has not been systematically compared with well-established stopping rules. The present study proposes a simulation with synthetic factor structures to compare NEST, parallel analysis, sequential test, Hull method, and the empirical Kaiser criterion.
View Article and Find Full Text PDFMetaverse-Aided Rehabilitation: A Perspective Review of Successes and Pitfalls.
J Clin Med
January 2025
Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences, University of Catanzaro "Magna Graecia", 88100 Catanzaro, Italy.
: The evolution of technology has continuously redefined the landscape of rehabilitation medicine. Researchers have long incorporated virtual reality (VR) as a promising intervention, providing immersive therapeutic environments for patients. The emergence of the metaverse has recently further expanded the potential applications of VR to augment the possibilities in rehabilitation.
View Article and Find Full Text PDFThiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2.
ACS Pharmacol Transl Sci
January 2025
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Schnackenburgallee 114, 22525 Hamburg, Germany.
The SARS-CoV-2 papain-like protease PLpro has multiple roles in the viral replication cycle, related to both its polypeptide cleavage function and its ability to antagonize the host immune response. Targeting the PLpro function is recognized as a promising mechanism to modulate viral replication, while supporting host immune responses. However, the development of PLpro-specific inhibitors remains challenging.
View Article and Find Full Text PDFPrecision Psychobiotics for Gut-Brain Axis Health: Advancing the Discovery Pipelines to Deliver Mechanistic Pathways and Proven Health Efficacy.
Microb Biotechnol
January 2025
Fonterra Microbiome Research Centre, University College Cork, Cork, Ireland.
Advancing microbiome-gut-brain axis science requires systematic, rational and translational approaches to bridge the critical knowledge gaps currently preventing full exploitation of the gut microbiome as a tractable therapeutic target for gastrointestinal, mental and brain health. Current research is still marked by many open questions that undermine widespread application to humans. For example, the lack of mechanistic understanding of probiotic effects means it remains unclear why even apparently closely related strains exhibit different effects in vivo.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!