Cysts of the tunica albuginea are uncommon lesions of the testis which in all reported cases have been benign. Complex cysts of the tunica albuginea can mimic intratesticular lesions, thus necessitating orchiectomy. We present a case of a complex tunica albuginea cyst which mimicked an intratesticular lesion at sonography, as well as at magnetic resonance imaging (MRI). Tangential views, however, suggested that this was in fact an extratesticular lesion. The use of tangential views, as well as knowledge of the appearance of the tunica albuginea at MRI, are important to make this differentiation in order to guide the management of these lesions. To our knowledge, this is the first case in which the appearance of a tunica albuginea cyst at MRI has been described.
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http://dx.doi.org/10.1007/BF02924606 | DOI Listing |
Sex Med
December 2024
Department of Clinical Research, University of Southern Denmark, 5000 Odense, Denmark.
Background: Peyronie's disease (PD) is a fibrotic disorder affecting the penile tunica albugínea, with unclear pathophysiology despite centuries of recognition.
Aim: This scoping review maps the effects of interventions in basic PD research, synthesizing evidence from in vivo and in vitro studies to guide future investigation.
Methods: In October-November 2023, a systematic search was conducted across PubMed, Embase (Ovid), Science of Web, and Scopus, following SRYCLE's guidelines.
J Sex Med
January 2025
Department of Urology, Holmesglen Private Hospital, Moorabbin 3189, Victoria, Australia.
Background: The penile suspensory ligament (PSL) plays a significant role in penile support and erection and its injury or congenital absence may result in functional impairment of erectile function.
Aim: To describe the diagnosis and surgical repair technique for PSL abnormalities and overall outcomes.
Methods: A comprehensive review of the literature was performed to understand the anatomic relevance of the PSL and historical management of PSL defects.
Paratesticular adenomatoid tumors are benign and rare neoplasms, and the management of these lesions is challenging as many cases end up in the operation room due to the lack of specific clinical and radiological features to differentiate them from malignant lesions. We report a case of adenomatoid tumor of the tunica albuginea in a 48-year-old male along with a review of the literature for similar cases in the last 10 years.
View Article and Find Full Text PDFJ Sex Med
December 2024
Department of Urology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, United States.
Background: Inflatable penile prosthesis (IPP) insertion is recommended for the treatment of patients with Peyronie's disease (PD) and significant erectile dysfunction (ED); adjunctive procedures can be used for residual curvature after IPP placement.
Aim: To assess the management of penile curvature correction in PD patients undergoing IPP procedures within a large multinational, multicenter cohort.
Methods: A retrospective analysis was conducted on PD patients treated with IPP by 11 experienced prosthetic surgeons.
BJU Int
December 2024
Fibrosis Research Group, Medical Technology Research Centre, Anglia Ruskin University, Chelmsford, UK.
Objectives: To investigate which phosphodiesterase (PDE) isoforms are expressed in fibroblasts isolated from the tunica albuginea (TA) of patients with Peyronie's disease (PD), and to measure the potency of PDE inhibitors in preventing transformation of these fibroblasts to profibrotic myofibroblasts.
Materials And Methods: Fibroblasts isolated from the TA of men undergoing surgery for correction of PD curvature were transformed to myofibroblasts using transforming growth factor beta-1. The expression of 21 PDE isoforms was investigated using quantitative reverse transcriptase-polymerase chain reaction and protein analysis, as were the effects of various PDE inhibitors on prevention of myofibroblast transformation.
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