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                            [content] => * Cilostazol (CZ) is an antiplatelet medication that helps reduce the risk of secondary strokes, acting on type 3 phosphodiesterase inhibition. *!  Research found that low doses of CZ did not relax dog cerebral arteries, but higher doses did so in an endothelium-independent way, while the relaxation from nerve stimulation depended on the endothelium. *!  CZ may enhance nitrergic nerve function in cerebral arteries through neuronal nitric oxide synthase (NOS) activation without interfering with noradrenergic nerve function, suggesting that its vasodilatory effects contribute to stroke prevention. *!
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