Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1373/clinchem.2008.107367 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Potential medical impact of unrecognized hypokalemia due to hemolysis: a case series.
Clin Chem Lab Med
September 2024
Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA.
Objectives: The destruction of red cells during blood collection or with the processing of the sample continues to occur at a high rate, especially among emergency department (ED) patients. This can produce pre-analytical laboratory errors, particularly for potassium. We determined the incidence of hemolyzed samples and discuss the potential medical impact for hypokalemic patients who potassium level is artificially normal (pseudoeukalemia).
View Article and Find Full Text PDFBackground: When CO escapes from plasma, the pH of the plasma increases. In samples left open or kept in long-term storage, the pH may increase considerably. Assays in which the ratio of plasma sample relative to the total volume including reagents is high may be sensitive to the pH of the plasma sample.
View Article and Find Full Text PDFNewborn Thyroid Screening: Influence of Pre-Analytic Variables on Dried Blood Spot Thyrotropin Measurement.
Thyroid
September 2017
3 Research Laboratories, i-calQ LLC , Salt Lake City, Utah.
Background: Measuring thyrotropin (TSH) eluted from a dried blood spot (DBS) is used to screen an estimated 30 million newborns annually for congenital hypothyroidism (CH). Newborn thyroid screening has eliminated cretinism from the industrialized world and decreased the adverse effects of unrecognized CH on neurocognitive development. Hematocrit, a pre-analytic variable that affects the measurement of TSH from a DBS, contributes to the imprecision of DBS TSH measurement and could account for false-negative and false-positive DBS newborn screening test results.
View Article and Find Full Text PDF"Proof of concept" pilot study: bioprocess chain of custody and bioresource sample management temperature observations. Sample level temperature trends and stability data obtained via utilization of bluechiip(®) temperature tracking technology.
Biopreserv Biobank
April 2013
1 Bluechiip Limited ("Bluechiip Ltd.").
Background: Preservation and optimization of biosample integrity to foster relevant research results and outcomes is a guiding principle of sample management. Tracking pre-analytical biospecimen lifecycle variables and bioprocessing chain of custody data enables documentation of adherence to best, regulatory and quality biobanking practices. Knowledge of individual sample and sample set temperature variability is believed to enhance delineation of artifacts during downstream analysis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!