Although abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patients with FD from the standpoint of bowel gas retention. The bowel gas volume calculated from a plain abdominal radiogram (gas volume score, GVS) in FD patients was significantly higher than that in healthy subjects. Two week administration of HKT in the FD patients showed a significant decrease of GVS. Furthermore, gastrointestinal symptoms, especially symptoms of abdominal pain, indigestion and constipation, all of which are closely related to abdominal bloating, improved significantly in FD patients after the administration of HKT. These results suggest that HKT improves abdominal bloating accompanied by the reduction of bowel gas in FD patients.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722198PMC
http://dx.doi.org/10.1093/ecam/nem101DOI Listing

Publication Analysis

Top Keywords

abdominal bloating
16
bowel gas
12
hangekobokuto banxia-houpo-tang
8
functional dyspepsia
8
hkt patients
8
gas volume
8
administration hkt
8
abdominal
6
patients
6
banxia-houpo-tang kampo
4

Similar Publications

Background: Irritable bowel syndrome (IBS) is influenced by various factors, including socioemotional stressors. The COVID-19 lockdown created a unique environment characterized by reduced social interactions, potentially impacting IBS symptoms.

Aim: To assess how lockdown measures affected symptoms related to the gut-brain axis in IBS patients in Buenos Aires, Argentina.

View Article and Find Full Text PDF

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report.

Front Pharmacol

December 2024

Pharmacy Department Nanjing Lishui People's Hospital, Zhongda Hospital Lishui Branch, Southeast University, Nanjing, Jiangsu Province, China.

Physical liver injury is an acute and potentially serious adverse event that may result in acute liver failure or even death. Diagnosis is often challenging. Minocycline, a semi-synthetic second-generation tetracycline, has high fat solubility and good tissue permeability.

View Article and Find Full Text PDF
Article Synopsis
  • A three-step scale called DICA was evaluated for its ability to predict diverticular disease in patients without symptoms during colorectal cancer screening.
  • In a study involving 3,879 participants, 24.7% were found to have diverticula, but the DICA scale did not show any significant relationship with the occurrence of diverticulitis or hospital admissions.
  • The study concluded that DICA has limited predictive value for diverticulitis, highlighting the need for further research with larger groups.
View Article and Find Full Text PDF
Article Synopsis
  • The study explores the relationship between small intestinal bacterial overgrowth (SIBO), irritable bowel syndrome (IBS), and inflammatory bowel diseases (IBD), stressing the potential benefits of diet therapy.
  • A literature review suggests that SIBO is commonly associated with IBS and shares symptoms like abdominal pain and bloating, implying potential overlaps between these conditions.
  • Increasing evidence links SIBO with IBD, particularly in Crohn's disease, highlighting the need for comprehensive treatment approaches that combine medication, psychotherapy, probiotics, and tailored dietary plans.
View Article and Find Full Text PDF

Malignant ascites (MA), a common and serious complication of various cancers in the abdominal cavity, originates from the extensive infiltration, metastasis, and growth of cancer cells in or on the abdominal cavity, leading to abnormal accumulation of fluid in the abdominal cavity and the formation of MA. MA seriously reduces the quality of life of cancer patients, shortens their survival period, and generally has a poor prognosis. Modern medicine has developed various strategies for the treatment of MA, including targeted supportive treatment, diuretic treatment, abdominal paracentesis, surgical intervention, and intraperitoneal administration therapy.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!