Free group II introns are infectious retroelements that can bind and insert themselves into RNA and DNA molecules via reverse splicing. Here we report the 3.4-A crystal structure of a complex between an oligonucleotide target substrate and a group IIC intron, as well as the refined free intron structure. The structure of the complex reveals the conformation of motifs involved in exon recognition by group II introns.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735234 | PMC |
| http://dx.doi.org/10.1038/nsmb.1509 | DOI Listing |
Publication Analysis
Top Keywords
exon recognition
8
recognition group
8
group introns
8
structure complex
8
structural basis
4
basis exon
4
group
4
group intron
4
intron free
4
free group
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!