Samples of the muscle and liver of the Nile tilapia (Oreochromis niloticus) were obtained from a single reservoir in each of three Sri Lankan catchments (Kaudulla, Rajanganaya, and Udawalawe reservoirs in the Mahaweli, Kala Oya, and Walawe Ganga river basins, respectively) in 2002. The concentrations of 12 elements were consistently detected in the tilapia muscle and liver (Ca, Cd, Cu, Fe, Hg, K, Mg, Mn, Na, P, Sr and Zn). However, a three factorial principal components analysis suggested that there were no differences in the metal profiles (range of elements and concentration) of the fish obtained from any of the three reservoirs, although the chemistries of each tissue (muscle and liver) were different. Metal concentrations were below WHO and Food Standards Australia and New Zealand guideline values, and substantial quantities of tilapia would need to be consumed each week on a regular basis to exceed intake limits (e.g. more than 1.5 kg to exceed intake lits for Cu), suggesting consumption of tilapia from these reservoirs poses little risk to human health.
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http://dx.doi.org/10.1007/s00128-008-9580-9 | DOI Listing |
Aging Cell
December 2024
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Aging is accompanied by multiple molecular changes that contribute to aging associated pathologies, such as accumulation of cellular damage and mitochondrial dysfunction. Tissue metabolism can also change with age, in part, because mitochondria are central to cellular metabolism. Moreover, the cofactor NAD, which is reported to decline across multiple tissues during aging, plays a central role in metabolic pathways such as glycolysis, the tricarboxylic acid cycle, and the oxidative synthesis of nucleotides, amino acids, and lipids.
View Article and Find Full Text PDFBMJ Case Rep
December 2024
Internal medicine, Canakkale Onsekiz Mart Universitesi Tip Fakultesi, Canakkale, Canakkale, Turkey.
Although hydatid cyst, caused by , can develop in any part of the body, involvement of the liver and lung represents approximately 90% of all cases. Involvement of the musculoskeletal system is comparatively rare. Diagnosis is difficult because symptoms are non-specific.
View Article and Find Full Text PDFToxicol Appl Pharmacol
December 2024
Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, 775 15 Olomouc, Czech Republic. Electronic address:
Cannabidiol (CBD) is a phytocannabinoid from Cannabis sativa L., in which there is currently growing interest for medicinal use. Here, we focused on the safety and pharmacokinetics of a CBD-rich (77 %, w/w) full-spectrum hemp extract in male and female rats.
View Article and Find Full Text PDFMetabolites
December 2024
Exercise Biological Research Center, China Institute of Sport Science, Beijing 100061, China.
Background: Insulin resistance (IR) is central to the progression of non-alcoholic fatty liver disease (MAFLD). While aerobic exercise reduces hepatic fat and enhances insulin sensitivity, the specific mechanisms-particularly those involving exosomal pathways-are not fully elucidated.
Method: Exosomes were isolated from 15 MAFLD patients' plasma following the final session of a 12-week aerobic exercise intervention.
Curr Issues Mol Biol
November 2024
Faculty of Health Sciences, Universidad San Jorge, Autov. A-23 Zaragoza-Huesca Km. 299, 50830 Villanueva de Gállego, Zaragoza, Spain.
Exercise, despite being a beneficial activity for health, can also be a source of oxidative imbalance, which can lead to a decrease in performance. Furthermore, melatonin is an endogenous molecule that may counteract exercise-induced oxidative stress. The aim of this study was to evaluate the potential ergogenic and antioxidant capacity of melatonin administered for a maximal effort test.
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