AI Article Synopsis
- The study examined the clinical characteristics of 122 multiple sclerosis (MS) patients diagnosed since 1978 at HUCFF/UFRJ, with a majority being females and Caucasian.
- The most common onset was relapsing-remitting MS, and Caucasians were more likely to experience a monosymptomatic onset compared to Afro-Brazilians.
- The mortality rate among the patients was low at 2.12%, with a notable association between the benign form of MS and the relapsing-remitting course.
Article Abstract
We studied the clinical and evolution characteristics of multiple sclerosis (MS) patients followed since the onset of HUCFF/UFRJ in 1978. The diagnosis of MS was based on Poser's et al. and MC Donald's et al. criteria. From 188 patients, 122 were included. Eighty-five were females. The mean age onset was 32.2 years-old (range 6.0 to 61.0+/-10.3), mainly Caucasians (82/67%). The relapsing-remitting course (MSRR) was more frequent (106/86.8%). Monosymptomatic onset was significantly more frequent in Caucasians than in Afro-Brazilians (p<0.05). Seventeen patients had benign form of MS and these patients presented association with MSRR when compared with severe form (p=0.01). The mortality rate was 2.12% (4 patients died). This study was similar to other Brazilian series with regard to sex and age, and lack of correlation between EDSS and number of relapses; it confirmed south-southeast African-descendants gradient distribution and association between first mono-symptomatic relapses and Caucasian; we found lower frequency of benign forms.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/s0004-282x2008000500012 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!