AI Article Synopsis
- A study of 534 patients with cerebral arteriovenous malformations treated using gamma knife radiosurgery (GKRS) showed high cumulative complete obliteration rates within 7 years, ranging from 92% for small volumes to 43% for larger volumes.
- Bleeding post-GKRS occurred in 8.1% of patients, with higher risks in those who had larger niduses and previous bleeding episodes.
- Cyst formation was observed in 4.7% of patients, with two-thirds requiring surgical intervention, indicating a need for improved GKRS techniques for more effective treatment outcomes.
Article Abstract
The Furukawa experience treating 534 patients with cerebral arteriovenous malformations using gamma knife radiosurgery (GKRS) is summarized. By repeating radiosurgery for any residual nidus after the first GKRS, the rates of cumulative complete obliteration 7 years after this initial GKRS, according to four volume categories (< or =1, 4 > or = >1, 10 > or = > 4, > 10cm3), were 92, 89, 68 and 43%, respectively. Bleeding after GKRS was observed in 8.1% of the patients and was more frequently seen in patients with a large nidus and history of bleeding two or more times before GKRS. Cyst formation was recognized in 4.7% of patients, two thirds of which required some form of surgical intervention. Refinement of the total GKRS system contributed to earlier and more effective nidus obliteration.
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| http://dx.doi.org/10.1159/000163379 | DOI Listing |
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