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Sex and Gender Considerations in Orthopaedic Research: Existing Barriers, What's Needed by Institutions and Research Departments, and How to Guide Junior Investigators and Faculty.
J Bone Joint Surg Am
October 2024
Office of Research on Women's Health, National Institutes of Health, Bethesda, Maryland.
JBJS convened a symposium to discuss the reporting of sex and gender in research studies as an imperative to improve research methods and results to benefit all patients. Barriers to improved reporting include a lack of societal and cultural acceptance of its need; a lack of education regarding appropriate terminology and appropriate statistical methods and efficient study designs; a need for increased research funding to support larger group sizes; unknown concordance of cell and animal models with humans to reflect biologic variables such as sex; and a lack of understanding of key considerations of gender, race, and other social determinants of health and how these factors intersect. Attention to developing and disseminating best-practice statistical methods and to educating investigators (at all career levels), reviewers, funders, editors, and staff in their proper implementation will aid reporting.
View Article and Find Full Text PDFWhat's new in the pediatric spine?
J Child Orthop
December 2024
Children's Orthopedic Center, Ankara, Turkey.
Introduction: The field of pediatric spine surgery has encountered major changes and evolutions lately, with new treatment options available and the development of enabling technologies. This article aims to summarize the most relevant recent literature.
Materials And Methods: The five most relevant topics were selected and assigned to one or two authors who performed a comprehensive Pubmed database search for articles published in the last 4 years (2021-2024).
New Immunosuppressants in Pediatric Kidney Transplantation: What's in the Pipeline for Kids?
Pediatr Transplant
February 2025
Department of Medicine III, Medical University of Vienna, Vienna, Austria.
The 1- and 5-year patient and graft survival rates of pediatric kidney transplant recipients have improved considerably in recent years. Regardless of early success, kidney transplantation is challenged by suboptimal long-term allograft and patient survival. Many kidney transplants are lost due to immune (rejection) and nonimmune allograft injuries, and patient survival is limited from cardiovascular disease, infection, and malignancy.
View Article and Find Full Text PDFDaily steps, cardiorespiratory fitness, and remnant cholesterol in schoolchildren: mediation effects for cardiovascular prevention.
Pediatr Res
December 2024
Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain.
Background: To analyse the associations between daily steps, cardiorespiratory fitness (CRF), and remnant cholesterol in schoolchildren and to investigate whether the association between daily steps and remnant cholesterol is mediated by CRF.
Methods: This cross-sectional study involved 394 schoolchildren (aged 9-12 years, 53.0% girls) from Cuenca, Spain.
Performance and physical activity. How playful activities implemented into training in Danish esports clubs influence players' performance experience.
Front Sports Act Living
December 2024
Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Introduction: Over the past few years, attention has focused on how physical activity can enhance esports players' performance. For example, complementing esports training with physical activities has been explored. However, most of these activities are based on traditional strength or endurance-related exercises, which do not align with the interests of children attending organized esports clubs.
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