The Enterobacter sakazakii is considered an emerging pathogen and has been recently connected to neonatal cases of necrotizing enterocolitis and meningitis due to use of contaminated powdered infant formula. However its presence is not limited to powdered infant formula; it can also be found in a broad range of foods and in water, in a variety of areas, including hospitals and houses. Due to the gravity of the infections attributed to E. sakazakii, it is necessary to introduce rigorous control measures to reduce the risks of contamination at various levels: industrial, to prevent from production to marketing the contamination of products; at a domestic level by reducing the risk of contamination, during preparation, handling, and storage, of reconstituted products; and legislative by establishing guidelines and recommendations issued by competent authorities, to guarantee the safety of infant food.
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J Bacteriol
December 2024
Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Unlabelled: The ability to treat infections is threatened by the rapid emergence of antibiotic resistance among pathogenic microbes. Therefore, new antimicrobials are needed. Here we evaluate mannitol-1-phosphate 5-dehydrogenase (MtlD) as a potential new drug target.
View Article and Find Full Text PDFFront Microbiol
December 2024
Department of Food and Animal Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Introduction: is a notorious foodborne pathogen, frequently contaminating powdered infant formula and causing life-threatening diseases in infants. The escalating emergence of antibiotics-resistant mutants has led to increased interest in using bacteriophage as an alternative antimicrobial agent.
Methods: Two phages, CR8 and S13, were isolated from feces and soil samples and their morphology, physiology, and genomics were characterized.
BMC Infect Dis
December 2024
Laboratoire de Biotechnologie des Molécules Bioactives et de la Physiopathologie Cellulaire (LBMBPC), Faculté des sciences de la Nature et de la vie, Université Batna 2, Batna, Algérie.
Background: Carbapenemase-producing Enterobacterales isolates are associated with significant mortality and have emerged as a major problem in healthcare settings worldwide.
Objective: Our aim was to investigate the epidemiological and genotypic characteristics of carbapenemase-positive Enterobacterales isolates from patients hospitalised in three hospitals in the city of Batna, Algeria.
Methods: Between 2016 and 2019, a total of 5,316 clinical isolates were obtained.
Foods
November 2024
School of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China.
is a dangerous pathogen easily found in powdered infant formula (PIF), causing severe infections and even death in infants. Herein, a bacteriophage-immobilized magnetic nanozyme (FeO@EspYZU13) was prepared for detection. Bacteriophage EspYZU13 isolated and identified by our group exhibits specific lytic capacity.
View Article and Find Full Text PDFJ Dairy Sci
December 2024
Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, 150030, China; Food Laboratory of Zhongyuan, Nanyang Institute of Technology, Luohe, 462300, China. Electronic address:
The objective of this study was to reveal the synergistic antibacterial activity and mechanism of Echinacea purpurea (L.) Moench crude extract (EE) and citric acid (CA) against Cronobacter sakazakii isolated from powdered infant formula (PIF). The minimum inhibitory concentration (MIC) of EE against C.
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