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Endoscopic Management of Benign Pancreaticobiliary Disorders.
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Division of Gastroenterology and Hepatology, Center for Digestive Health, Virginia Mason, Franciscan Health, Seattle, WA 98101, USA.
Endoscopic management of benign pancreaticobiliary disorders encompasses a range of procedures designed to address complications in gallstone disease, choledocholithiasis, and pancreatic disorders. Acute cholecystitis is typically treated with cholecystectomy or percutaneous drainage (PT-GBD), but for high-risk or future surgical candidates, alternative decompression methods, such as endoscopic transpapillary gallbladder drainage (ETP-GBD), and endoscopic ultrasound (EUS)-guided gallbladder drainage (EUS-GBD), are effective. PT-GBD is associated with significant discomfort as well as variable adverse event rates.
View Article and Find Full Text PDFTraditional Chinese Medicine-Based Nanoformulations for Enhanced Photothermal Therapy of Cancer.
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Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, P. R. China.
Photothermal therapy (PTT) has shown promise in the ablation of small, unresectable tumors by boosting the tumor's temperature above 50 °C. However, the high local temperature-induced cancer cell necrosis could create severe local inflammation, which may deteriorate normal tissues and increase tumor spreading. Although mild photothermal therapy (MPTT) at 42-45 °C could avoid the undesired side effect to some extent with minimal nonspecific heat diffusion, the self-protective behavior of tumors during MPTT results in an unsatisfactory therapeutic effect.
View Article and Find Full Text PDFLentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice.
AMB Express
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Department of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, 116044, China.
Chemotherapeutic therapies for cancer are frequently associated with cytotoxic side effects that can be harmful to human health, including the development of intestinal mucositis (IM). It mostly affects the gastrointestinal tract, causing ulceration, inflammation, and the formation of lesions in the colon. Surprisingly, despite the frequency of IM, therapeutic choices remain restricted.
View Article and Find Full Text PDFRace Against the Clock: Severe Acute Abdominal Pain With Disastrous Complications.
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Pulmonary, Critical Care and Sleep Medicine, University of New Mexico Hospitals, Albuquerque, USA.
Although a rare medical condition, gastric ischemia is a medical emergency and requires prompt recognition. Current literature review is scarce, with a primary focus on iatrogenic, surgical, and vascular etiologies. The cases discussed focus on hypoperfusion secondary to refractory shock as the etiology of gastric ischemia and, unfortunately, death.
View Article and Find Full Text PDFEfficient in-droplet cell culture and cytomechanics measurement for assessment of human cellular responses to alcohol.
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Robotics and Microsystems Center, School of Mechanical and Electrical Engineering, Soochow University, Suzhou, 215000, China. Electronic address:
Background: Excessive alcohol consumption poses a significant threat to human health, leading to cellular dehydration, degeneration, and necrosis. Alcohol-induced cellular damage is closely linked to alterations in cellular mechanical properties. However, characterizing these changes following alcohol-related injury remains challenging.
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